16289-54-6Relevant articles and documents
The synthesis of 5-substituted 1H-tetrazoles in molten tetrabutylammonium bromide
Xie, Aming,Cao, Meiping,Feng, Liandong,Dong, Wei
, p. 665 - 667 (2013)
An economical and environmentally benign method for the synthesis of 5-substituted 1H-tetrazoles has been established. In this protocol, molten tetrabutylammonium bromide (TBAB) is used as both the solvent and catalyst. A mechanism involving the intermedi
Why is tetrazole formation by addition of azide to organic nitriles catalyzed by zinc(II) salts?
Himo, Fahmi,Demko, Zachary P.,Noodleman, Louis,Sharpless, K. Barry
, p. 9983 - 9987 (2003)
The mechanism by which zinc(II) catalyzes the union of an azide ion with organic nitriles to form tetrazoles is investigated by means of density functional theory using the hybrid functional B3LYP. The calculations indicate that coordination of the nitril
Synthesis, crystal structure and catalytic property of a new samarium compound derived from 5-(pyrazin-2-yl)tetrazole-2-acetic acid
Zou, Jian-Hua,Chen, Dian-Yu,Yang, Gao-Wen,Li, Qiao-Yun,Yang, Jie,Shen, Lei
, p. 27887 - 27890 (2015)
[Sm(pztza)2(H2O)6]·pztza·3H2O has been prepared by the reaction of SmCl3·6H2O and 5-(pyrazin-2-yl)tetrazole-2-acetic acid (Hpztza) under the presence of potassium hydroxide. The compound has been structurally characterized by elemental analysis, IR, and single-crystal X-ray diffraction. The X-ray analysis demonstrates this complex displays a mononuclear structure. Furthermore, it shows an excellent catalytic property for polymerization of vinyl monomers and the polymerization shows controlled characteristics. It can be isolated from the reaction system and reused at least 10 times.
Fe3O4@L-lysine-Pd(0) organic–inorganic hybrid: As a novel heterogeneous magnetic nanocatalyst for chemo and homoselective [2 + 3] cycloaddition synthesis of 5-substituted 1H-tetrazoles
Ashraf, Muhammad Aqeel,Liu, Zhenling,Li, Cheng,Zhang, Dangquan
, (2020/12/23)
An efficient and sustainable synthetic protocol has been presented to synthesis and 5-substituted 1H-tetrazole privileged heterocyclic substructures. The synthetic protocol involves two-component reaction between aryl nitriles and NaN3 in water using complex of L-lysine-palladium nanoparticles (NPs) modified Fe3O4 nanoparticles as magnetically separable, recyclable, and reusable heterogeneous catalyst. Magnetically retrievable L-lysine-Pd(0) modified Fe3O4 nanoparticles were applied in [2 + 3] cycloaddition synthesis of 5-substituted 1H-tetrazoles. The advantages of this strategy include easy recovery and efficient reusability of the expensive Pd NPs, obtaining high yields of [2 + 3] cycloaddition, short reaction times, and all of the reported synthetic strategies are being performed in water as green solvent for a wide range of substrates.
Urea mediated 5-substituted-1H-tetrazole via [3?+?2] cycloaddition of nitriles and sodium azide
Yakambram,Jaya Shree,Srinivasula Reddy,Satyanarayana,Naveen,Bandichhor, Rakeshwar
supporting information, p. 445 - 449 (2018/01/03)
A simple, new and convenient metal free procedure for the synthesis of 5-substituted 1H-tetrazoles using various nitriles and sodium azide in the presence of urea and acetic acid with good to high yields is developed. The reaction plausibly proceeds through in situ formation of urea azide active complex without toxic and/or expensive metal catalysts.