162971-77-9

Basic information

• Product Name: 2-Hydroxy-3-(2-methyl-2-propenyl)benzaldehyde
• Synonyms: 2-Hydroxy-3-(2-methyl-2-propenyl)benzaldehyde;2-Hydroxy-(3-(2-Methyl)allyl)benzaldehyde;2-hydroxy-3-(2-methyl-2-propen-1-yl)Benzaldehyde
• CAS NO: 162971-77-9
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.21
• Mol File: 162971-77-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 261℃
• Flash Point: 108℃
• Appearance: /
• Density: 1.099
• Vapor Pressure: 0.00748mmHg at 25°C
• Refractive Index: 1.579
• PKA: 8.29±0.35(Predicted)
• CAS DataBase Reference: 2-Hydroxy-3-(2-methyl-2-propenyl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-3-(2-methyl-2-propenyl)benzaldehyde(162971-77-9)
• EPA Substance Registry System: 2-Hydroxy-3-(2-methyl-2-propenyl)benzaldehyde(162971-77-9)

Safety Data

• Hazardous Substances Data: 162971-77-9(Hazardous Substances Data)

Usage

General Description

2-Hydroxy-3-(2-methyl-2-propenyl)benzaldehyde is a unique chemical compound with the molecular formula C11H12O2. It belongs to the class of organic compounds known as benzaldehydes, which are aromatic compounds containing a benzene ring in which one of the carbon atoms is substituted with a formyl (aldehyde) group. Specifically, it is characterized by the presence of a hydroxy group and a 2-methyl-2-propenyl group attached to the benzene ring. Like many benzaldehydes, this compound may have various applications in chemical research and synthesis. As it has an aldehyde group, it has the properties of a carbonyl compound and, with the presence of hydroxy group, it can potentially exhibit the capabilities of an alcohol too. However, specific properties and potential applications may depend on its precise chemical behavior, which can be influenced by surrounding conditions and reactions with other compounds.

InChI:InChI=1/C11H12O2/c1-8(2)6-9-4-3-5-10(7-12)11(9)13/h3-5,7,13H,1,6H2,2H3

Upstream product

• 90-02-8 salicylaldehyde 
• 38002-87-8 O-methallylsalicylaldehyde 

Downstream Products

• 1381841-09-3 C₂₇H₃₅N₇O₄S₂ 
• 1359964-95-6 2-(2-(2-hydroxy-3-(2-methylallyl)benzylidene)hydrazinyl)-4-(4-methoxyphenyl)pyrido[2,3-b]pyrazin-3(4H)-one 
• 1359964-65-0 2-(2-(2-hydroxy-3-(2-methylallyl)benzylidene)hydrazinyl)-4-phenylpyrido[2,3-b]pyrazin-3(4H)-one 
• 1359965-12-0 2-(2-(2-hydroxy-3-(2-methylallyl)benzylidene)hydrazinyl)-4-(4-(trifluoromethoxy)phenyl)pyrido[2,3-b]pyrazin-3(4H)-one 
• 38002-88-9 2,3-dihydro-2,2-dimethylbenzofuran-7-carboxaldehyde 

Relevant articles and documents

Synthesis and cytotoxic activity of novel 2,6-disubstituted-4-mor- pholinothieno[3,2-d]pyrimidines as potent anti-tumor agents

A series of 2,6-disubstituted-4-morpholinothieno[3,2-d]pyrimidine derivatives were synthesized and their cytotoxic activity against H460, HT-29, MDA-MB-231, U87MG and H1975 cancer cell lines were evaluated in vitro. Most of the target compounds exhibited moderate to excellent activity to the tested cell lines. The most promising compound 23 (0.84 μmol/L, 0.23 μmol/L, 2.52 μmol/L, 1.80 μmol/L) was 1.0, 2.9, 29.3 and 4.3 times more active than GDC-0941 (0.87 μmol/L, 0.66 μmol/L, 73.8 μmol/L, 7.77 μmol/L) against H460, HT-29, MDA-MB-231 and U87MG cell lines, respectively.