1635-09-2

Basic information

• Product Name: N-dodecyl-p-toluenesulphonamide
• Synonyms: N-dodecyl-p-toluenesulphonamide;N-Dodecyl-4-methylbenzenesulfonamide
• CAS NO: 1635-09-2
• Molecular Formula: C₁₉H₃₃NO₂S
• Molecular Weight: 339.53582
• EINECS: 216-657-3
• Mol File: 1635-09-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 73 °C
• Boiling Point: 450.6°Cat760mmHg
• Flash Point: 226.3°C
• Appearance: /
• Density: 1.004g/cm³
• Vapor Pressure: 2.61E-08mmHg at 25°C
• Refractive Index: 1.5
• PKA: 11.82±0.50(Predicted)
• CAS DataBase Reference: N-dodecyl-p-toluenesulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-dodecyl-p-toluenesulphonamide(1635-09-2)
• EPA Substance Registry System: N-dodecyl-p-toluenesulphonamide(1635-09-2)

Safety Data

• Hazardous Substances Data: 1635-09-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H33NO2S/c1-3-4-5-6-7-8-9-10-11-12-17-20-23(21,22)19-15-13-18(2)14-16-19/h13-16,20H,3-12,17H2,1-2H3

Upstream product

• 124-22-1 n-Dodecylamine 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 106-33-2 ethyl laurate 
• 70-55-3 toluene-4-sulfonamide 
• 112-53-8 1-dodecyl alcohol 
• 56079-38-0 N,N-di(p-toluenesulfonyl)dodecylamine 
• 159690-31-0 1-p-Toluolsulfonyl-1-phenethyl-hydrazin 
• 146404-40-2 1-tosyl-1-hexadecylhydrazine 
• 146404-41-3 C₁₅H₁₇ClN₂O₂S 
• 141666-87-7 1-Tosyl-1-<2-(4-methoxyphenyl)ethyl>hydrazine 
• 141666-92-4 4-methyl-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide 
• 141666-91-3 N-[2-(4-chlorophenyl)ethyl]-4-methylbenzenesulfonamide 
• 18049-99-5 N-hexadecyl-p-toluenesulfonamide 
• 5450-75-9 4-methyl-N-(2-phenylethyl)benzenesulfonamide 

Downstream Products

• 5450-75-9 4-methyl-N-(2-phenylethyl)benzenesulfonamide 
• 18049-99-5 N-hexadecyl-p-toluenesulfonamide 
• 1950-69-2 toluene-p-sulfonyl bromide 
• 143-15-7 1-dodecylbromide 
• 141666-91-3 N-[2-(4-chlorophenyl)ethyl]-4-methylbenzenesulfonamide 
• 141666-92-4 4-methyl-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide 
• 141666-87-7 1-Tosyl-1-<2-(4-methoxyphenyl)ethyl>hydrazine 
• 146404-41-3 C₁₅H₁₇ClN₂O₂S 
• 146404-40-2 1-tosyl-1-hexadecylhydrazine 
• 98-59-9 p-toluenesulfonyl chloride 
• 112-52-7 1-chlorododecane 
• 159690-31-0 1-p-Toluolsulfonyl-1-phenethyl-hydrazin 
• 1208109-23-2 N-dodecyl-N-t-butoxycarbonyl-p-toluenesulfonamide 
• 1208109-24-3 N-dodecyl-N-(6-(tetrahydro-2H-pyran-2-yloxy)hexyl)-p-toluenesulfonamide 

Relevant articles and documents

Synthesis, Characterization, and Reactivity of an Ethynyl Benziodoxolone (EBX)-Acetonitrile Complex

The synthesis of a crystalline ethynyl-1,2-benziodoxol-3(1H)-one (EBX)-acetonitrile complex is described. EBX has been widely used as an active species for a variety of reactions; however, its high instability has so far prevented its isolation. The EBX-acetonitrile is self-assembled into a double-layered honeycomb structure through weak hypervalent iodine secondary interactions and hydrogen bonding. The N-ethynylation of a variety of sulfonamides using the EBX-acetonitrile complex as a substrate under mild conditions is also described.

NAlkylation of tosylamides using esters as primary and tertiary alkyl sources: Mediated by hydrosilanes activated by a ruthenium catalyst

Select your group: Either a primary or tertiary alkyl group can be selectively introduced onto the nitrogen atom of tosylamides in a ruthenium-catalyzed reaction employing hydrosilanes through a judicious choice in the esters that serve as the alkyl source (see scheme; Ts= 4-toluenesulfonyl). These N-alkylation reactions are useful for construction of naturally occurring azacyclic skeletons. Copyright

Hg cathode-free electrochemical detosylation of N,N-disubstituted p-toluenesulfonamides: mild, efficient, and selective removal of N-tosyl group

Hg cathode-free electrochemical detosylation of N,N-disubstituted p-toluenesulfonamides was successfully carried out by a constant current electrolysis using an undivided cell equipped with a platinum cathode and a magnesium anode in the presence of an arene mediator. The deprotection proceeded efficiently and selectively under neutral and mild conditions with a stoichiometric amount of electricity without the use of an Hg cathode to obtain the corresponding secondary amines in good to excellent yields.