16356-05-1

Basic information

• Product Name: 3,4-dimethylidenehexane
• Synonyms: 2,3-Diethyl-1,3-butadiene
• CAS NO: 16356-05-1
• Molecular Formula: C₈H₁₄
• Molecular Weight: 110.1968
• Mol File: 16356-05-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 124.5°C at 760 mmHg
• Flash Point: 15.7°C
• Density: 0.732g/cm³
• Vapor Pressure: 15.3mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: 3,4-dimethylidenehexane(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethylidenehexane(16356-05-1)
• EPA Substance Registry System: 3,4-dimethylidenehexane(16356-05-1)

Safety Data

• Hazardous Substances Data: 16356-05-1(Hazardous Substances Data)

Upstream product

• 16356-08-4 3-ethoxymethyl-penta-1,2-diene 
• 925-90-6 ethylmagnesium bromide 
• 18265-39-9 (E,E)-3,4-dimethylhexa-2,4-diene 
• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 1185-02-0 3,4-dimethyl-3,4-hexanediol 
• 7732-18-5 water 
• 108-86-1 bromobenzene 
• 23074-36-4 2-bromobutene 

Downstream Products

• 19550-88-0 trans-3,4-Dimethyl-3-hexene 
• 19550-87-9 cis-3,4-Dimethyl-3-hexene 

Relevant articles and documents

β-turn and β-hairpin mimicry with tetrasubstituted alkenes

Synthesis and conformational analysis are reported for molecules containing the trans-5-amino-3,4-dimethylpent-3-enoic acid residue (ADPA, 1). This amino acid is a glycylglycine mimic, in which the central amide group is replaced with an E-tetrasubstituted alkene. It was anticipated that this isosteric replacement would promote specific local (β-turn) and nonlocal (β-hairpin) conformational preferences. Previous work has shown that the most common β-turn conformations (type I and type II) are not strong inducers of β-hairpin formation, while the rare 'mirror image' β-turns (type I' and type II') promote β-hairpin formation. We therefore sought an achiral unit with a strong turn-forming propensity, since the lack of stereogenic centers within such a unit would eliminate the energetic distinction between common and 'mirror image' turn conformations. In, the ADPA unit, avoidance of allylic strain was expected to preorganize the backbone for adoption of folded conformations. A combination of NMR and IR data for di-, tri-, and tetrapeptide analogues containing the ADPA residue reveal that β-turn- and β-hairpin-like folding is promoted in methylene chloride solution.

IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

The present invention provides a novel imidazole derivative having the chemical formula STR1 These compounds are useful for preventing or treating hypertension or congestive heart failure and have high activity, rapid action upon intravenous injection, go

Chemical process

Novel 2,4-dihydrocarbylspiro[5.5]undeca-1,4,8-trien-3-one compounds are prepared by reacting an N,N-dihydrocarbyl,2,6-dihydrocarbyl-4-aminomethylphenol with a conjugated diene and an alkyl halide in a liquid solvent medium.