1636158-19-4

Basic information

• Product Name: (E)-dimethyl 2-[2-(4-phenylbut-3-en-1-yl)benzylidene]-malonate
• CAS NO: 1636158-19-4
• Molecular Weight: 350.414
• Mol File: 1636158-19-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-dimethyl 2-[2-(4-phenylbut-3-en-1-yl)benzylidene]-malonate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-dimethyl 2-[2-(4-phenylbut-3-en-1-yl)benzylidene]-malonate(1636158-19-4)
• EPA Substance Registry System: (E)-dimethyl 2-[2-(4-phenylbut-3-en-1-yl)benzylidene]-malonate(1636158-19-4)

Safety Data

• Hazardous Substances Data: 1636158-19-4(Hazardous Substances Data)

Upstream product

• 4392-24-9 Cinnamyl bromide 
• 108-59-8 malonic acid dimethyl ester 
• 1636157-86-2 C₁₉H₂₁NO 
• 6639-19-6 N,N,2-trimethylbenzamide 

Relevant articles and documents

Scandium-catalyzed cascade cyclization to produce cyclobutane-fused tetrahydroquinoline, chromane, thiochromane, and tetrahydronaphthalene derivatives

We have succeeded in the highly diastereoselective synthesis of cyclobutane-fused multi-cyclic compounds using a scandium-catalyzed cascade cyclization. Using 3-10 mol% of scandium(III) triflate [Sc(OTf)3], various cyclobutane-fused tetrahydroquinoline derivatives as well as its chromane, thiochromane, and tetrahydronaphthalene analogues were obtained in good to excellent yields. Derivatizations of the reaction products, as well as the plausible reaction mechanism, are also discussed.