163837-58-9

Basic information

• Product Name: 1-[(S)-(4-Chloro-phenyl)-phenyl-methyl]-4-(toluene-4-sulfonyl)-piperazine
• CAS NO: 163837-58-9
• Molecular Weight: 440.994
• Mol File: 163837-58-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(S)-(4-Chloro-phenyl)-phenyl-methyl]-4-(toluene-4-sulfonyl)-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(S)-(4-Chloro-phenyl)-phenyl-methyl]-4-(toluene-4-sulfonyl)-piperazine(163837-58-9)
• EPA Substance Registry System: 1-[(S)-(4-Chloro-phenyl)-phenyl-methyl]-4-(toluene-4-sulfonyl)-piperazine(163837-58-9)

Safety Data

• Hazardous Substances Data: 163837-58-9(Hazardous Substances Data)

Upstream product

• 439695-63-3 (R_S,S)-(1-(4-chlorophenyl)-1-phenylmethyl)-2-methylpropanesulfinamide 
• 336105-23-8 (R)-(-)-N-[(1E)-(4-chlorophenyl)methylene]-2-methyl-2-propanesulfinamide 
• 186249-76-3 (R,E)-2-methyl-N-(phenylmethylene)-2-propanesulfinamide 
• 100-52-7 benzaldehyde 
• 104-88-1 4-chlorobenzaldehyde 
• 42137-88-2 N,N-bis(2-chloroethyl)-p-toluenesulfonamide 
• 163837-32-9 (S)-4-chloro-α-phenyl-benzenemethanamine 

Downstream Products

• 246870-46-2 (S)-(-)-cetirizine ethyl ester 
• 130018-87-0 (+)-Cetirizine dihydrochloride 
• 439858-21-6 1-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazine 

Relevant articles and documents

Asymmetric synthesis of cetirizine dihydrochloride

Practical route technology for the preparation of (S)-cetirizine·2HCl via diastereoselective organometallic addition to N-tert-butanesulfinyl aldimines is disclosed.