1642-85-9

Basic information

• Product Name: 1H-2-Benzopyran-1-one, 8-hydroxy-3-methyl-
• CAS NO: 1642-85-9
• Molecular Formula: C10H8O3
• Molecular Weight: 176.172
• Mol File: 1642-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran-1-one, 8-hydroxy-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran-1-one, 8-hydroxy-3-methyl-(1642-85-9)
• EPA Substance Registry System: 1H-2-Benzopyran-1-one, 8-hydroxy-3-methyl-(1642-85-9)

Safety Data

• Hazardous Substances Data: 1642-85-9(Hazardous Substances Data)

Usage

Uses

+ Flavoring agent in food and beverages
+ Fragrance ingredient in perfumes and cosmetics

Medicinal properties

+ Anti-inflammatory
+ Antioxidant
+ Anti-cancer

Role in medication production

Interferes with blood clotting for anticoagulant effects

Industry applications

Wide range of uses and potential benefits in various industries.

Upstream product

• 204066-34-2 3-(1-hydroxyethyl)-7-methoxyphthalide 

Downstream Products

• 101445-89-0 8-benzoyloxy-3-methyl-isocoumarin 

Relevant articles and documents

Reactions of 3-(1-Hydroxyalkyl)phthalides with Acids: Synthesis of (Z)-3-Alkylidenephthalides and 3-Alkyl-8-hydroxyisocoumarins

A new acid-catalyzed method for the synthesis of (Z)-3-butylidenephthalides 5 and a novel and general route to 3-alkyl-8-hydroxy/methoxyisocoumarins 6-8 from phthalides 9 is described. The hydroxyphthalides 4 and 10 were obtained by condensation of the phthalide anion with butyraldehyde and acetaldehyde. Reaction of hydroxyphthalides 4 with a mixture of orthophosphoric acid and formic acid gave the (Z)-3-butylidenephthalides 5, while the hydroxyphthalides 4 and 10 on reaction with p-toluenesulfonic acid provided the 3-alkylisocoumarins 6-8. The present approaches permit variation of the 3-substituent in isocoumarin and the pattern of functionalization on the aromatic rings of both isocoumarins and alkylidenephthalides.