1642336-21-7Relevant articles and documents
Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development
Brouwer, Chad,Jenko, Kimberly J.,Zoghbi, Sami S.,Morse, Cheryl L.,Innis, Robert B.,Pike, Victor W.
, p. 677 - 688 (2016/09/16)
Modifications to an N-methyl-(quinolin-4-yl)oxypropanamide scaffold were explored to discover leads for developing new radioligands for PET imaging of brain TSPO (translocator protein), a biomarker of neuroinflammation. Whereas contraction of the quinolin