16441-34-2

Basic information

• Product Name: (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER
• Synonyms: ethyl 2-(2-phenylthiazol-4-yl)acetate;ETHYL 2-(2-PHENYL-1,3-THIAZOL-4-YL)ACETATE;(2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER
• CAS NO: 16441-34-2
• Molecular Formula: C₁₃H₁₃NO₂S
• Molecular Weight: 247.31
• Mol File: 16441-34-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 377.1 °C at 760 mmHg
• Flash Point: 181.9 °C
• Appearance: /
• Density: 1.196 g/cm³
• Vapor Pressure: 6.89E-06mmHg at 25°C
• Refractive Index: 1.57
• Storage Temp.: 2-8°C
• PKA: 1.15±0.10(Predicted)
• CAS DataBase Reference: (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER(16441-34-2)
• EPA Substance Registry System: (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER(16441-34-2)

Safety Data

• Hazardous Substances Data: 16441-34-2(Hazardous Substances Data)

Usage

General Description

(2-Phenyl-thiazol-4-yl)-acetic acid ethyl ester is a chemical compound with the molecular formula C12H11NO2S. It is an ethyl ester derivative of (2-phenyl-thiazol-4-yl)-acetic acid, which is a thiazole derivative. (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER is commonly used in organic synthesis and pharmaceutical research. It may have potential applications in drug development and medicinal chemistry due to its structural and functional properties. However, further research is needed to fully understand its potential uses and biological activities.

InChI:InChI=1/C13H13NO2S/c1-2-16-12(15)8-11-9-17-13(14-11)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3

Upstream product

• 638-07-3 ethyl (2-chloroaceto)acetate 
• 2227-79-4 benzenecarbothioamide 
• 13176-46-0 4-bromoethyl acetoacetate 

Downstream Products

• 64483-96-1 2-(2-phenylthiazol-4-yl)ethan-1-ol 
• 645393-01-7 2-(2-phenylthiazol-4-yl)ethan-1-amine 

Relevant articles and documents

Synthesis and Antimicrobial Screening of 2-Aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

A new series of 2-aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives was synthesized by condensation of 2-(2-substituted thiazol-4-yl)acetohydrazide with aryl aldehydes followed by oxidative cyclocondensation using iodobenzene diacetate. The

Synthesis and Antifungal Screening of 2-(2-Aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

(Chemical Equation Presented) A new series of synthesis and biological screening of 2-(2-aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives 5a-i was achieved by condensation of 2-(2-aryl/benzylthiazol-4-yl)aceto

Development of new thiazole-based iridium catalysts and their applications in the asymmetric hydrogenation of trisubstituted olefins

New thiazole-based chiral N,P-ligands that are open-chain analogues of known cyclic thiazole ligands have been synthesized and evaluated in the iridium-catalyzed asymmetric hydrogenation of trisubstituted olefins. Chirality was introduced into the ligands through a highly diastereoselective alkylation using Oppolzer's camphorsultam as chiral auxiliary. In general, the new catalysts are as reactive and selective as their cyclic counterparts for the asymmetric hydrogenation of various trisubstituted olefins. This journal is The Royal Society of Chemistry.