164453-64-9 Usage
General Description
2,5-Piperazinedione,3,6-diethyl-,(3S-cis)-(9CI) is a chemical compound with the molecular formula C10H16N2O2. It is also known as cis-3,6-diethyl-2,5-piperazinedione and is used as an intermediate in the synthesis of pharmaceuticals and organic compounds. 2,5-Piperazinedione,3,6-diethyl-,(3S-cis)-(9CI) is a white solid at room temperature and has a molecular weight of 192.25 g/mol. It is important to handle this chemical with care, as it may cause irritation to the skin, eyes, and respiratory system upon exposure. Furthermore, it should be stored in a cool, dry place and kept away from sources of ignition and incompatible materials.
Check Digit Verification of cas no
The CAS Registry Mumber 164453-64-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,4,4,5 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 164453-64:
(8*1)+(7*6)+(6*4)+(5*4)+(4*5)+(3*3)+(2*6)+(1*4)=139
139 % 10 = 9
So 164453-64-9 is a valid CAS Registry Number.
164453-64-9Relevant articles and documents
Chemo-Enzymic Synthesis of Optically Active α,α-Disubstituted α-Amino Acids
Liu, Weiguo,Ray, Paul,Benezra, Steven A.
, p. 553 - 560 (2007/10/02)
A series of α,α-disubstituted α-amino esters was chemically synthesized and then resolved through enantioselective hydrolysis catalysed by a new enzyme isolated from crude Humicola langinosa lipase.This enzyme only accepts free amino esters as substrates with neither lipase activity toward olive oil nor esterase activity toward o-nitrophenyl butyrate.It is unique in that it successfully catalyses the resolution of amino esters with two large α-alkyl groups including aliphatic, aromatic and cyclic amino esters.Examples of resolutions where the alkyl groups differ in size by as little as a single carbon atom have been demonstrated.For determination of absolute configuration, some of the optically active α,α-disubstituted amino acids were also prepared through Schoellkopf's asymmetric synthesis and the structures were verified by X-ray crystallography.A model depicting the substrate binding site of the enzyme is proposed.
