16486-98-9 Usage
Description
1-CHLORO-8-IODOPERFLUOROOCTANE, with the CAS number 16486-98-9, is a fluoroalkylation agent characterized by its unique chemical structure that incorporates both chlorine and iodine atoms within an octane backbone. 1-CHLORO-8-IODOPERFLUOROOCTANE is known for its reactivity and stability, making it a valuable component in various chemical reactions and synthetic processes.
Uses
1-CHLORO-8-IODOPERFLUOROOCTANE is used as a fluoroalkylation agent for the synthesis of chiral fluorine-containing γ-butyrolactones. The application reason is its ability to introduce fluorine atoms into organic molecules, which can significantly alter their physical and chemical properties, leading to improved pharmaceutical and chemical performance.
Used in Pharmaceutical Industry:
1-CHLORO-8-IODOPERFLUOROOCTANE is used as a synthetic building block for the development of novel pharmaceutical compounds. The application reason is its potential to enhance the properties of drug candidates, such as increasing their bioavailability, stability, and selectivity towards specific biological targets.
Used in Chemical Industry:
1-CHLORO-8-IODOPERFLUOROOCTANE is used as a reagent in the preparation of various specialty chemicals and materials. The application reason is its versatility in fluoroalkylation reactions, which can lead to the creation of new compounds with unique properties for use in various applications, such as lubricants, surfactants, and polymers.
Check Digit Verification of cas no
The CAS Registry Mumber 16486-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,4,8 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16486-98:
(7*1)+(6*6)+(5*4)+(4*8)+(3*6)+(2*9)+(1*8)=139
139 % 10 = 9
So 16486-98-9 is a valid CAS Registry Number.
InChI:InChI=1/C8ClF16I/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
16486-98-9Relevant articles and documents
Practical and efficient synthesis of perfluoroalkyl iodides from perfluoroalkyl chlorides via modified sulfinatodehalogenation
Cao, Hai-Ping,Chen, Qing-Yun
, p. 1187 - 1190 (2008/02/10)
A novel two-step one pot synthesis of perfluoroalkyl iodides (α,ω-diiodoperfluoroalkanes) from perfluoroalkyl chlorides (α-chloro-ω-iodoperfluoroalkanes) has been developed by initial conversion to the corresponding sodium perfluoroalkanesulfinates with sodium dithionite and then subsequent oxidation by iodine.
Copper-Induced Telomerization of Tetrafluoroethylene with Fluoroalkyl Iodides
Chen, Qing-Yun,Su, De-Bao,Yang, Zhen-Yu,Zhu, Rong-Xian
, p. 483 - 489 (2007/10/02)
In the presence of catalytic amounts of copper, telomerization of tetrafluoroethylene with fluoroalkyl iodides can be carried out at 80-100 deg C.As compared with usual high-temperature (200 deg C) telomerization process, the reaction time required is much shorter.
