165074-34-0

Basic information

• Product Name: N-(phenylsulfonylimino)-3-phenylpyridinium ylide
• Synonyms: N-(phenylsulfonylimino)-3-phenylpyridinium ylide
• CAS NO: 165074-34-0
• Molecular Weight: 310.376
• Mol File: 165074-34-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(phenylsulfonylimino)-3-phenylpyridinium ylide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(phenylsulfonylimino)-3-phenylpyridinium ylide(165074-34-0)
• EPA Substance Registry System: N-(phenylsulfonylimino)-3-phenylpyridinium ylide(165074-34-0)

Safety Data

• Hazardous Substances Data: 165074-34-0(Hazardous Substances Data)

Upstream product

• 1008-88-4 3-phenylpyridine 
• 135055-48-0 N-(2',4'-dinitrophenyl)-3-phenylpyridinium chloride 
• 80-17-1 benzenesufonyl hydrazide 

Relevant articles and documents

Synthesis of Some N-(Phenylsulfonylamino)-1,2,3,6-tetrahydropyridines as Potential Anti-inflammatory Agents

Several N-(phenylsulfonylamino)-1,2,3,6-tetrahydropyridines were synthesized by substituting a sulfonyl group for the carbonyl group of N-(phenylcarbonylamino)-1,2,3,6-tetrahydropyridines 1 in order to investigate the effect of the substitution on the analgesic and anti-inflammatory activities. Nucleophilic attack of pyridine derivatives 2 on 1-chloro-2,4-dinitrobenzene 3 furnished the pyridinium chlorides 4. Compound 4 and benzenesulfonyl hydrazide 5 were reacted to give the 2,4-dinitroanilino derivatives 6. Hydrolysis of 6 furnished the ylides 7. Sodium borohydride reduction of ylides afforded the tetrahydropyridines 8. Compound 8c was found to be the most active anti-inflammatory agent and was as potent as indomethacin, the reference compound. Compound 8f had the most significant hyperglycemic activity.