165668-35-9Relevant articles and documents
Synthesis and biological evaluation of N-(7-indazolyl)benzenesulfonamide derivatives as potent cell cycle inhibitors
Bouissane,El Kazzouli,Leonce,Pfeiffer,Rakib,Khouili,Guillaumet
, p. 1078 - 1088 (2007/10/03)
We herein describe a new synthesis of N-(7-indazolyl)benzenesulfonamide derivatives. These compounds were evaluated for their antiproliferative activities toward L1210 murine leukemia cells. One of them, 4-methoxy-N-(3- chloro-7-indazolyl)benzenesulfonamide, was identified as the most potent with an IC50 of 0.44 μM.
New and efficient synthesis of bi- and trisubstituted indazoles
Bouissane, Latifa,El Kazzouli, Sa?d,Léger, Jean-Michel,Jarry, Christian,Rakib, El Mostapha,Khouili, Mostafa,Guillaumet, Gérald
, p. 8218 - 8225 (2007/10/03)
In this paper, the synthesis of bi- and trisubstituted indazoles was described. 4-Alkoxy-7-aminoprotected-indazole or 7-aminoprotected-indazole derivatives were prepared selectively using SnCl2 in alcohol or SnCl2 in ethyl acetate, r