165679-43-6

Basic information

• Product Name: 2-(2-Fluoro-phenyl)-6-methoxy-benzo[e][1,3]oxazin-4-one
• Synonyms: 2-(2-Fluoro-phenyl)-6-methoxy-benzo[e][1,3]oxazin-4-one
• CAS NO: 165679-43-6
• Molecular Weight: 271.248
• Mol File: 165679-43-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-Fluoro-phenyl)-6-methoxy-benzo[e][1,3]oxazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Fluoro-phenyl)-6-methoxy-benzo[e][1,3]oxazin-4-one(165679-43-6)
• EPA Substance Registry System: 2-(2-Fluoro-phenyl)-6-methoxy-benzo[e][1,3]oxazin-4-one(165679-43-6)

Safety Data

• Hazardous Substances Data: 165679-43-6(Hazardous Substances Data)

Upstream product

• 393-52-2 2-Fluorobenzoyl chloride 
• 28534-37-4 2-hydroxy-5-methoxybenzamide 

Relevant articles and documents

Synthesis of Some 2-Aryl-1,2,4-triazolobenzoxazin-5-ones as Tools To Define the Essential Pharmacophoric Descriptors of a Benzodiazepine Receptor Ligand

The synthesis and benzodiazepine receptor (BZR) affinity of some 1,2,4-triazolo-benzoxazin-5-ones, 2-22, are reported.Compounds 2-22 are devoid of the proton donor group, which according to a BZR schematic model was one of the pharmacophoric descriptors for receptor-ligand interaction.The binding data show that 2-(2-fluorophenyl)-9-chloro-1,2,4-triazolobenzoxazin-5-one (12) and some other compounds display nanomolar BZR affinity, indicating that the hydrogen donor group is not essential for the anchoring of 6,6,5-tricyclic systems to the BZR but only affects the potency of a ligand.