16578-60-2

Basic information

• Product Name: [3-(hydroxymethyl)-2-nitrophenyl]methanol
• Synonyms: [3-(hydroxymethyl)-2-nitrophenyl]methanol
• CAS NO: 16578-60-2
• Molecular Weight: 183.164
• Mol File: 16578-60-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: [3-(hydroxymethyl)-2-nitrophenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(hydroxymethyl)-2-nitrophenyl]methanol(16578-60-2)
• EPA Substance Registry System: [3-(hydroxymethyl)-2-nitrophenyl]methanol(16578-60-2)

Safety Data

• Hazardous Substances Data: 16578-60-2(Hazardous Substances Data)

Usage

Description

[3-(hydroxymethyl)-2-nitrophenyl]methanol, with the chemical formula C8H9NO4, is a yellow powder compound characterized by a molecular weight of 179.16 g/mol. It is recognized for its anti-inflammatory and analgesic properties, making it a significant compound in the fields of research and pharmaceutical development.

Uses

Used in Organic Synthesis:
[3-(hydroxymethyl)-2-nitrophenyl]methanol is utilized as a reagent in organic synthesis, contributing to the creation of various chemical compounds and products.
Used in Pharmaceutical Production:
[3-(hydroxymethyl)-2-nitrophenyl]methanol also serves as an intermediate in the pharmaceutical industry, playing a vital role in the development and manufacturing of different medications.
Used in Research and Drug Development:
Due to its anti-inflammatory and analgesic properties, [3-(hydroxymethyl)-2-nitrophenyl]methanol is a valuable asset in research and drug development, potentially leading to the discovery of new treatments and therapies.
Safety Precautions:
When handling [3-(hydroxymethyl)-2-nitrophenyl]methanol, it is essential to take safety precautions, as this chemical may cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 57052-99-0 dimethyl 2-nitroisophthalate 
• 21161-11-5 2-nitroisophthalic acid 
• 81-20-9 2,6-dimethylnitrobenzene 

Downstream Products

• 1392043-94-5 4-(3-(acryloyloxymethyl)-2-nitrobenzyloxy)-4-oxobutanoic acid 
• 1392043-93-4 2-acryloxymethyl-6-hydroxymethyl-nitrobenzene 
• 1447147-11-6 C₅₈H₄₄N₆O₁₆ 
• 1447146-95-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl 2,6-bis(hydroxymethyl)phenylcarbamate 
• 1447146-92-0 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl 2,6-bis((tert-butyldimethylsilyloxy)methyl)phenylcarbamate 
• 1447146-90-8 2,6-bis((tert-butyldimethylsilyloxy)methyl)aniline 
• 1447146-88-4 2,6-bis((tert-butyldimethylsilyloxy)methyl)aniline 
• 1422174-98-8 2-nitrobenzyl (2,6-bis(hydroxymethyl)phenyl)carbamate 
• 1378860-88-8 (2-amino-1,3-phenylene)dimethanol 
• 936943-02-1 2-nitro-3-(tert-butyldimethylsilyloxymethyl)-hydroxymethylbenzene 
• 99641-32-4 diethyl 3,3'-(2-nitro-1,3-phenylene)bis(2-propenoate) 
• 99320-75-9 2-nitro-1,3-benzenedialdehyde 

Relevant articles and documents

Multistimuli-responsive hydrogel particles prepared via the self-assembly of PEG-based hyperbranched polymers

Generally, it is very difficult to obtain multistimuli-responsive hydrogel particles. Here, we introduce a novel method for the preparation of multistimuli-responsive hydrogel particles by adding water into the poly(ethylene glycol) (PEG)-based hyperbranched polymers. The produced PEG-base polymers via reversible addition-fragmentation chain transfer (RAFT) polymerization become temperature-sensitive and less soluble when heated above the lower critical solution temperature (LCST) after directly adding water. Subsequently, the hydrogel particles can be formed via hyperbranch-hyperbranch coupling through disulfide exchange. The resulting hydrogel particles are temperature-, photo-, and redox-responsive.

Photodegradable bridged silane and preparation method thereof

The invention relates to photodegradable bridged silane and a preparation method thereof. The photodegradable bridged silane has a structure as shown in a formula I which is described in the specification. The method comprises the following steps: taking 1, 3-dimethyl-2-nitrobenzene as a raw material, carrying out oxidation reaction to obtain 2-nitro 1, 3-phthalic acid, carrying out reduction reaction on a carboxylic acid group to obtain 2-nitro-1, 3-benzenedimethanol, carrying out acylation reaction on the 2-nitro-1, 3-benzenedimethanol and chloroacetyl chloride to obtain 2-nitro-1, 3-benzenedichloroacetate, and finally carrying out substitution reaction on the 2-nitro-1, 3-benzenedichloroacetate and amino-containing silane to obtain the photodegradable bridged silane containing 2-nitrobenzyl. The photodegradable bridged silane obtained in the invention has good photoresponse performance, can be used for designing and preparing photoresponsive functional materials, and has important application value. The synthesis process is simple, raw materials are easy to obtain, reaction conditions are mild, and operability is high.

Programmed photodegradation of polymeric/oligomeric materials derived from renewable bioresources

Renewable polymeric materials derived from biomass with built-in phototriggers were synthesized and evaluated for degradation under irradiation of UV light. Complete decomposition of the polymeric materials was observed with recovery of the monomer that was used to resynthesize the polymers.