16620-75-0

Basic information

• Product Name: Benzenemethanimine, 4-methyl-a-(4-methylphenyl)-
• Synonyms: 4,4'-Dimethyl-benzophenon-imin;C-Di-p-tolyl-methyleneamine;bis(para-tolyl)methanimine;bis(4-methylphenyl)ketimine;4,4'-dimethyl-benzophenone-imine;di-p-tolylmethanimine;bis(4-methylphenyl)methanimine
• CAS NO: 16620-75-0
• Molecular Formula: C15H15N
• Molecular Weight: 209.291
• Mol File: 16620-75-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 67-69 °C
• Boiling Point: 130 - 135 °C (0.2 mmHg)
• Density: 0.98±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanimine, 4-methyl-a-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanimine, 4-methyl-a-(4-methylphenyl)-(16620-75-0)
• EPA Substance Registry System: Benzenemethanimine, 4-methyl-a-(4-methylphenyl)-(16620-75-0)

Safety Data

• Hazardous Substances Data: 16620-75-0(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 104-85-8 para-methylbenzonitrile 
• 611-97-2 bis(p-methylphenyl)-methanone 
• 4294-57-9 para-methylphenylmagnesium bromide 

Downstream Products

• 611-97-2 bis(p-methylphenyl)-methanone 
• 68968-77-4 C₂₇H₂₄NP 
• 95023-64-6 3,3-Di-p-tolyl-2-cyan-acrylsaeure-amid 
• 67157-21-5 C₁₆H₁₇NS 
• 71339-61-2 C₂₂H₂₀N₂O₂S 
• 71339-62-3 C₂₂H₂₀N₂O₃S 
• 67174-47-4 Di-p-tolylmethylene-methoxymethyl-amine 
• 69414-82-0 N'-Di-p-tolylmethylene-N'-,N'-dimethyl-methanediamine 
• 21236-73-7 N-Pikryl-di-(p-tolyl)-methylen-imin 
• 31158-16-4 C₂₁H₁₈ClNS 
• 67157-22-6 C₂₂H₂₁NS 
• 71339-58-7 C₂₂H₂₁NS 
• 67157-24-8 C₁₆H₁₄Cl₃NS 
• 71339-63-4 C₁₉H₂₃NS 

Relevant articles and documents

Scandium(III) Triflate Catalyzed Direct Synthesis of N-Unprotected Ketimines

N-Unprotected ketimines are useful substrates and intermediates for synthesizing valuable nitrogen-containing compounds, but their potential applicability is limited by the available synthetic methods. To address this issue, we report a scandium(III) triflate catalyzed direct synthesis of N-unprotected ketimines. Using commercially available reagents and Lewis acid catalysts, ketones were directly transformed into the corresponding N-unprotected ketimines in high yields with broad functional group tolerance, even in multigram scales. The reactions were readily applicable for one-pot synthesis of important compounds such as a glycine Schiff base without isolation of N-unprotected ketimine intermediates. Preliminary mechanistic studies to clarify the reaction mechanism are also described.

Selective Oxidative [4+2] Imine/Alkene Annulation with H2 Liberation Induced by Photo-Oxidation

The oxidative [4+2] annulation reaction represents an elegant and versatile synthetic protocol for the construction of six-membered heterocyclic compounds. Herein, a photoinduced oxidative [4+2] annulation of NH imines and alkenes was developed by utilizing a dual photoredox/cobaloxime catalytic system. Various multisubstituted 3,4-dihydroisoquinolines can be obtained in good yields. This method is not only obviated the need of stiochiometric amounts of oxidants but also exhibited excellent atom economy by generating H2 as the only byproduct. Remarkably, high regioselectivity and trans diastereoselectivity can be achieved in this transformation even if the Z/E mixture of alkenes were employed.

Pd-catalyzed enantioselective C-H iodination: Asymmetric synthesis of chiral diarylmethylamines

An enantioselective C-H iodination reaction using a mono-N-benzoyl- protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.