16637-13-1

Basic information

• Product Name: Acetamide, N-[2,6-bis(1-methylethyl)phenyl]-
• Synonyms: 2,6-diisopropylacetanilide;HMS1396C22;2,6-iPr2C6H3NHC(O)Me;N-(2,6-diisopropylphenyl)acetamide;2,6-di-(iPr)2C6H3NHAc;Essigsaeure-(2,6-diisopropyl-anilid);acetic acid-(2,6-diisopropyl-anilide);Acetanilide,2,6-diisopropyl
• CAS NO: 16637-13-1
• Molecular Formula: C14H21NO
• Molecular Weight: 219.327
• Mol File: 16637-13-1.mol
• Article Data: 16

Chemical Properties

• Melting Point: 198-200 °C(Solv: dichloromethane (75-09-2); ligroine (8032-32-4))
• Boiling Point: 338.4±31.0 °C(Predicted)
• Density: 0.984±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Acetamide, N-[2,6-bis(1-methylethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2,6-bis(1-methylethyl)phenyl]-(16637-13-1)
• EPA Substance Registry System: Acetamide, N-[2,6-bis(1-methylethyl)phenyl]-(16637-13-1)

Safety Data

• Hazardous Substances Data: 16637-13-1(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 24544-04-5 2,6-diisopropylbenzenamine 
• 62-53-3 aniline 
• 75-36-5 acetyl chloride 
• 2162-74-5 N,N'-bis(2,6-diisopropylphenyl)carbodiimide 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 1355445-67-8 C₆H₃(CH(CH₃)2)2NCCH₃OP(C(CH₃)3)2 
• 1355445-68-9 C₆H₃(CH(CH₃)2)2NCOCH₃P(C(CH₃)3)2 
• 1355445-63-4 C₆H₃(CH(CH₃)2)2NCCH₃OP(CH(CH₃)2)2 
• 1355445-64-5 C₆H₃(CH(CH₃)2)2NCOCH₃P(CH(CH₃)2)2 
• 110694-44-5 3-chloro-2,6-diisopropylbenzenamine 
• 304865-77-8 N-(2,6-diisopropylphenyl)-acetimidoyl chloride 

Relevant articles and documents

Manganese(I) Catalyzed α-Alkenylation of Amides Using Alcohols with Liberation of Hydrogen and Water

Herein, unprecedented manganese-catalyzed direct α-alkenylation of amides using alcohols is reported. Aryl amides are reacted with diverse primary alcohols, which provided the α,β-unsaturated amides in moderate to good yields with excellent selectivity. Mechanistic studies indicate that Mn(I) catalyst oxidizes the alcohols to their corresponding aldehydes and also plays an important role in efficient C═C bond formation through aldol condensation. This selective olefination is facilitated by metal-ligand cooperation by the aromatization-dearomatization process operating in the catalytic system. Biorenewable alcohols are used as alkenylation reagents for the challenging α-alkenylation of amides with the highly abundant base metal manganese as a catalyst, which results in water and dihydrogen as the only byproduct, making this catalytic transformation attractive, sustainable, and environmentally benign.

Iron Tridentate Carbene Single Site Catalysts

The present disclosure provides iron-containing catalyst compounds having a carbene ligand. Catalyst compounds of the present disclosure can be asymmetric, having an electron donating side of the catalyst and an electron deficient side of the catalyst. In

Acylation of Phenols, Alcohols, Thiols, Amines and Aldehydes Using Sulfonic Acid Functionalized Hyper-Cross-Linked Poly(2-naphthol) as a Solid Acid Catalyst

Abstract: The hyper-cross-linked porous poly(2-naphthol) fabricated by the Friedel–Crafts alkylation of 2-naphthol has been functionalized with sulfonic acid to obtain a solid acid catalyst. The catalyst is applied for the protection of phenol, alcohols, thiols, amines and aldehydes with acetic anhydride at room temperature. The catalytic protection using the new solid acid is featured by achieving high yield at neat condition, needing no aqueous work-up and/or chromatographic separation, and showing excellent recycling efficiency, suggesting the potential of this sulfonated porous polymers as a new protection protocol in a wide range of sustainable chemical reactions. Graphical Abstract: [Figure not available: see fulltext.].