166593-11-9Relevant articles and documents
Ambivalent nucleophilicity of 1,4,5-trisubstituted imidazole-2-thiones in reactions with dimethyl acetylenedicarboxylate and phenylisocyanate
Mloston,Gendek,Linden,Heimgartner
, p. 1561 - 1569 (2008/12/23)
The 1,4,5-trisubstitued 2,3-dihydro-1H-imidazole-2-thiones 1 react with electrophilic reagents via the S- or the N(3)-atom. The reaction with dimethyl acetylenedicarboxylate in methanol at room temperature occurs by the nucleophilic addition of the S-atom
Novel imidazoles and hydantoins moderately strained by incorporation with 2-azabicyclo[2.2.1]heptene skeleton
Kobayashi,Fujieda,Murakami,Nakamura,Ono,Yamamoto,Kato
, p. 3082 - 3087 (2007/10/02)
The reactions of 3-acyl-2-azabicyclo[2.2.1]hept-5-enes with phenyl isocyanate, phenyl isothiocyanate, and ethoxycarbonyl isothiocyanate followed by cyclization reactions under basic conditions respectively provided a hydantoin, a thiohydantoin, and a 1,3-