1666-85-9

Basic information

• Product Name: 1,3,4-TRIPHENYL-1H-PYRAZOLE
• Synonyms: 1,3,4-TRIPHENYL-1H-PYRAZOLE;1,3,4-triphenylpyrazole
• CAS NO: 1666-85-9
• Molecular Formula: C₂₁H₁₆N₂
• Molecular Weight: 296.37
• Product Categories: pharmacetical
• Mol File: 1666-85-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 443 °C at 760 mmHg
• Flash Point: 221.7 °C
• Appearance: /
• Density: 1.08 g/cm³
• Vapor Pressure: 1.25E-07mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 1,3,4-TRIPHENYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-TRIPHENYL-1H-PYRAZOLE(1666-85-9)
• EPA Substance Registry System: 1,3,4-TRIPHENYL-1H-PYRAZOLE(1666-85-9)

Safety Data

• Hazardous Substances Data: 1666-85-9(Hazardous Substances Data)

Usage

Description

1,3,4-Triphenyl-1H-pyrazole is a chemical compound with a molecular formula C21H15N3. It is a type of pyrazole derivative and belongs to the class of organic compounds known as phenylpyrazoles. 1,3,4-TRIPHENYL-1H-PYRAZOLE is characterized by its unique structure, which features a pyrazole ring fused with three phenyl groups. It has been studied for its potential pharmaceutical and biological activities, as well as its potential use in the development of new drugs.

Uses

Used in Pharmaceutical and Biological Research:
1,3,4-Triphenyl-1H-pyrazole is used as a building block in the synthesis of other organic compounds for pharmaceutical and biological research. Its unique structure and properties make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Fluorescent Sensor Development:
1,3,4-Triphenyl-1H-pyrazole is known for its ability to exhibit fluorescence, making it a useful component in the development of fluorescent sensors. These sensors can be designed to detect metal ions, which have various applications in research, environmental monitoring, and other fields.
Used in Organic Synthesis:
1,3,4-Triphenyl-1H-pyrazole is used as a key intermediate in the synthesis of various organic compounds. Its versatile structure allows for the creation of a wide range of molecules with different properties and potential applications in various industries.

InChI:InChI=1/C21H16N2/c1-4-10-17(11-5-1)20-16-23(19-14-8-3-9-15-19)22-21(20)18-12-6-2-7-13-18/h1-16H

Upstream product

• 77987-92-9 Phenyl-(2,4,5-triphenyl-3,4-dihydro-2H-pyrazol-3-yl)-methanone oxime 
• 40110-66-5 (E)-2-phenyl-1-(phenylsulfinyl)ethene 
• 15424-14-3 N-phenylbenzohydrazonoyl chloride 
• 16212-06-9 phenyl styryl sulfone 
• 501-65-5 diphenyl acetylene 
• 508191-77-3 3-phenylsydnone 
• 100-52-7 benzaldehyde 
• 100-63-0 phenylhydrazine 
• 5153-67-3 nitrostyrene 
• 588-64-7 (E)-1-benzylidene-2-phenylhydrazine 
• 108-86-1 bromobenzene 
• 77169-12-1 1,3-diphenyl-1H-pyrazole-4-carboxylic acid 
• 583-11-9 N-(1-phenylethylidene)phenylhydrazine 
• 21487-45-6 1,3-diphenyl-4-formylpyrazole 

Relevant articles and documents

-

-

Synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines via cascade imination/intramolecular decarboxylative coupling

A general approach for the synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines is described involving the implementation of a cascade imination/intramolecular decarboxylative coupling between potassium 2-amino(hetero)benzoates and 2-haloarylaldehydes. The reactions of pyrazole-based substrates require a Pd-Cu bimetallic system for superior yields whereas the thienyl-based substrates afford the products in excellent yields with a Pd-catalyst only.

Regioselective rapid analog synthesis of 1,3-(or 1,5-)diphenyl-4-aryl/ heteroaryl-5-(or 3-)(methylthio)pyrazoles via Suzuki cross-coupling

Regioselective routes for the synthesis of 1,3-(or 1,5-)diphenyl-4-aryl/ heteroaryl-5-(or 3-)(methylthio)pyrazoles via Suzuki cross-coupling of 4-bromo (or 4-iodo)-1,3-(or 1,5-)diphenyl-5-(or 3-)(methylthio)pyrazoles have been reported.