16669-00-4Relevant articles and documents
SYNTHESIS OF HYPERVALENT IODINE REAGENTS WITH DIOXYGEN
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Paragraph 0105-0106, (2019/01/15)
Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.
Catalyst-Free Aromatic Radiofluorination via Oxidized Iodoarene Precursors
Kwon, Young-Do,Son, Jeongmin,Chun, Joong-Hyun
supporting information, p. 7902 - 7906 (2019/01/04)
Oxidized iodoarenes (OIAs), prepared via mCPBA-mediated oxidation, have been demonstrated as versatile precursors for the synthesis of [18F]fluoroarenes in the absence of catalysts. OIAs have been identified as intermediates in single-pot syntheses of iodonium salts and ylides but have never been recognized as radiofluorination precursors. Here, the isolated OIAs were used without any catalysts to produce functionalized [18F]fluoroarenes, regardless of the electronic nature of the arenes. This method was also applied to the production of radiolabeling synthons for use as aromatic 18F-labeled building blocks.
RuCl3-catalyzed oxidation of iodoarenes with peracetic acid: New facile preparation of iodylarenes
Koposov, Alexey Y.,Karimov, Rashad R.,Pronin, Andrey A.,Skrupskaya, Tatyana,Yusubov, Mekhman S.,Zhdankin, Viktor V.
, p. 9912 - 9914 (2007/10/03)
New facile methodology for the preparation of pentavalent iodine compounds using peracetic acid as an oxidant in the presence of catalytic amounts of ruthenium trichloride is described. The new procedure allows the preparation of several previously unknown iodylarenes bearing strongly electron-withdrawing CF3 groups in the aromatic ring.
