1668-08-2

Basic information

• Product Name: L-GALACTONO-1,4-LACTONE
• Synonyms: L(+)-GALACTONIC ACID GAMMA-LACTONE;L-GALACTONIC ACID GAMMA LACTONE;L(+)-GALACTONO-1,4-LACTONE;L-GALACTONO-1,4-LACTONE;GAMMA-L-GALACTONOLACTONE;Galactonolactone;L(+)-GALACTONICACIDG-LACTONE;L-(+)-Galactonic acid γ-lactone
• CAS NO: 1668-08-2
• Molecular Formula: C₆H₁₀O₆
• Molecular Weight: 178.14
• Mol File: 1668-08-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 134-136 °C
• Boiling Point: 467.939 °C at 760 mmHg
• Flash Point: 201.545 °C
• Appearance: /
• Density: 1.766 g/cm³
• Vapor Pressure: 1.01E-10mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: ?20°C
• PKA: 12.06±0.60(Predicted)
• BRN: 83005
• CAS DataBase Reference: L-GALACTONO-1,4-LACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: L-GALACTONO-1,4-LACTONE(1668-08-2)
• EPA Substance Registry System: L-GALACTONO-1,4-LACTONE(1668-08-2)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 1668-08-2(Hazardous Substances Data)

Usage

Description

L-Galactono-1,4-lactone is an organic compound with the chemical formula C6H8O6. It is a white powder and serves as a substrate for various biochemical reactions and investigations.

Uses

Used in Enzyme Research:
L-Galactono-1,4-lactone is used as a substrate for the investigation of an L-Fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily. This application is crucial for understanding the function and mechanism of this specific enzyme, which can contribute to the broader knowledge of enzymatic processes and potential applications in biotechnology or pharmaceuticals.
Used in Chemical Synthesis:
As an organic compound, L-Galactono-1,4-lactone can be utilized in chemical synthesis for the production of various derivatives and related compounds. Its unique structure allows it to be a valuable building block in the creation of complex molecules with potential applications in different industries, such as pharmaceuticals, agrochemicals, or materials science.
Used in Analytical Chemistry:
The white powder form of L-Galactono-1,4-lactone makes it suitable for use in analytical chemistry as a reference material or standard for the calibration of instruments and methods. Its distinct chemical properties can be employed to validate the accuracy and precision of analytical techniques, ensuring reliable results in research and quality control processes.
Used in Pharmaceutical Development:
Given its role as a substrate in enzyme research, L-Galactono-1,4-lactone may have potential applications in the development of new pharmaceuticals. Understanding the interactions between this compound and various enzymes could lead to the discovery of novel drug targets or the design of more effective therapeutic agents.
Used in Material Science:
The unique chemical structure of L-Galactono-1,4-lactone may also find applications in material science, particularly in the development of new polymers or materials with specific properties. Its potential use in this field could lead to the creation of innovative materials with applications in various industries, such as electronics, automotive, or aerospace.

InChI:InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3-,4-,5+/m0/s1

Upstream product

• 685-73-4 D-galacturonic acid 
• 19242-59-2 D-galactose N,N'-diphenylformazan 
• 608-66-2 D-galactitol 
• 133-42-6 galactonic acid 
• 69-65-8 mannitol 
• 133-42-6 L-galactonic acid 

Downstream Products

• 643-01-6 L-mannitol 
• 50-99-7 galactose 
• 133-42-6 gluconic acid 
• 50-81-7 ascorbic acid 
• 490-83-5 L-dehydroascorbic acid 
• 13074-06-1 L-fucitol 
• 73-34-7 6-deoxy-L-galactose 
• 138332-00-0 6-azido-L-galactose 
• 70932-38-6 1,2:3,4-di-O-isopropylidene-6-O-(p-toluenesulfonyl)-α-L-galactopyranose 
• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-L-galactopyranose 
• 124819-01-8 L-galactono-1,5-lactone 
• 1426415-12-4 (3S,4R,6S)-3,4-O-isopropylidene-6-(tosyloxymethyl)tetrahydro-2H-pyran-3,4-diol 
• 1426415-10-2 (3S,4R,6S)-3,4-O-isopropylidene-6-(3,5-dinitrobenzoyloxymethyl)tetrahydro-2H-pyran-3,4-diol 
• 91548-32-2 L-lyxo-[2]hexulosonic acid 

Related news

Ascorbic acid in pollen: Conversion of L-GALACTONO-1,4-LACTONE (cas 1668-08-2) to L-ascorbic acid by Lilium longiflorum☆09/25/2019

The L-ascorbic acid (AA) content of pollen from three cultivars of Lilium longiflorum Thunb. was 260–280 μg/g fresh wt. of pollen. During germination ascorbic acid content gradually decreased reaching 70% of the original value at 6 h. Pollen germinated in media containing 0.29 M D-glucose (an ...detailed

Liquid crystalline 5,6-O-acetals of L-GALACTONO-1,4-LACTONE (cas 1668-08-2) prepared by a microwave irradiation on montmorillonite09/24/2019

Acetal derivatives of L-galactono-1,4-lactone showing thermotropic liquid crystalline properties were synthesized without sovent in the presence of dry montmorillonite KSF using microwave irradiation.detailed

l-Ascorbate biosynthesis in strawberries: L-GALACTONO-1,4-LACTONE (cas 1668-08-2) dehydrogenase expression during fruit development and ripening09/09/2019

l-Galactono-1,4-lactone dehydrogenase (GLDH; E.C. 1.3.2.3), the enzyme responsible for the last step of l-ascorbate biosynthesis in plants, was cloned from strawberries (Fragaria × ananassa Duch, cv. Campineiro) and its activity and expression followed during fruit development and ripening. Pro...detailed

PhysiologyTiller number is altered in the ascorbic acid-deficient rice suppressed for L-GALACTONO-1,4-LACTONE (cas 1668-08-2) dehydrogenase09/08/2019

The tiller of rice (Oryza sativa L.), which determines the panicle number per plant, is an important agronomic trait for grain production. Ascorbic acid (Asc) is a major plant antioxidant that serves many functions in plants. l-Galactono-1,4-lactone dehydrogenase (GLDH, EC 1.3.2.3) is an enzyme ...detailed

Alterations in Ascorbic Acid Levels by Transformation of the L-GALACTONO-1,4-LACTONE (cas 1668-08-2) Dehydrogenase Gene in Solanum tuberosum09/07/2019

L-galactono-1, 4-lactone dehydrogenase (GLDH) is an important enzyme that catalyzes the last step of the ascorbate biosynthetic pathways in plants. A full-length cDNA clone encoding GLDH was isolated from potato (Solanum tuberosum L. ‘Favorita’) leaf and subcloned into a binary vector, pBI121,...detailed

Relevant articles and documents

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METHOD FOR PRODUCING L-FUCOSE

The present invention provides: in a first aspect, a method for the preparation of L-fucose, wherein L-fucose precursors are produced from pectin and L-fucose is produced from the L-fucose precursors; in a second aspect, a method for the preparation of L-fucose from D-galacturonic acid or a salt thereof, wherein L-fucose precursors are produced from D-galacturonic acid or a salt thereof, and L-fucose is produced from the L-fucose precursors; and an L-fucose precursoras shown in Formula A below, wherein R is a linear or branched chain saturated hydrocarbon group with 1-6 carbon atoms, such as methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, s-butyl, t-butyl, n-hexyl, etc., preferably a methyl group.

2-Acetamido-2-deoxyaldonolactones from sugar formazans

A new approach towards simple aldonic acid derivatives starting from the corresponding aldoses via the 2-acetamido-2-deoxy formazans resulted in the synthesis of 2-acetamido-2-deoxy-D-galactono-1,4-lactone (8), and its 6-deoxy (11) and 6-azido-6-deoxy (14) analogues on treatment with trifluoroacetic acid.The five-membered ring structure of the lactones and that of the intermediate lactone phenylhydrazone (7) was proved by 1H and 13C NMR studies, including deuterium-induced differential isotope shift (DIS) measurements.With sodium borohydride, lactones 8 and 11 were converted into 2-acetamido-2-deoxy-D-galactitol (15) and its 6-deoxy analogue (17), respectively.