1668-82-2Relevant articles and documents
STUDY OF THE ASYMMETRIC INDUCTION OF THE 1,3-DIPOLAR CYCLOADDITION OF CHIRAL AZOMETHINE YLIDES WITH UNACTIVATED DOUBLE BONDS
Negron, Guillermo,Roussi, Georges,Zhang, Jidong
, p. 293 - 301 (2007/10/02)
The asymmetric induction of the 1,3-dipolar cycloaddition reaction between nonstabilized azomethine ylides generated by deprotonation of the corresponding tertiary amine N-oxides (1a-f) with a base and various unactivated olefins (2a-c) or dienes (2d-e) h
Reaction of alkyl sulfoxides and phenylphosphinic acid with amines. Alternative reagents for secondary amines N-alkylation
Chauvin
, p. 1425 - 1428 (2007/10/02)
Phenylphosphinic acid and dialkylsulfoxides are found to be alternative reagents for respectively the reducing reagent (formic acid) and the alkylating reagent (aldehyde) currently used for secondary amines N-alkylation. Primary amines do not react with this system, but phenylglycine is decarboxilated to benzylamine.