1669-51-8

Basic information

• Product Name: 4'-BROMO-3-PHENYLPROPIOPHENONE
• Synonyms: UKRORGSYN-BB BBV-5118724;4'-BROMO-3-PHENYLPROPIOPHENONE
• CAS NO: 1669-51-8
• Molecular Formula: C₁₅H₁₃BrO
• Molecular Weight: 289.17
• Mol File: 1669-51-8.mol
• Article Data: 62

Chemical Properties

• Boiling Point: 403.8°C at 760 mmHg
• Flash Point: 76.6°C
• Appearance: /
• Density: 1.349g/cm³
• Vapor Pressure: 9.9E-07mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 4'-BROMO-3-PHENYLPROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BROMO-3-PHENYLPROPIOPHENONE(1669-51-8)
• EPA Substance Registry System: 4'-BROMO-3-PHENYLPROPIOPHENONE(1669-51-8)

Safety Data

• Hazardous Substances Data: 1669-51-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H13BrO/c16-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-5,7-10H,6,11H2

Upstream product

• 2403-27-2 1-(4-bromophenyl)-3-phenyl-2-propen-1-one 
• 72758-69-1 (E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one 
• 58824-56-9 1-(p-bromophenyl)prop-2-en-1-ol 
• 98-80-6 phenylboronic acid 
• 100-52-7 benzaldehyde 
• 99-73-0 para-bromophenacyl bromide 
• 5391-88-8 1-(4-bromophenyl)ethanol 
• 100-51-6 benzyl alcohol 
• 99-90-1 para-bromoacetophenone 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 100-42-5 styrene 
• 1122-91-4 4-bromo-benzaldehyde 
• 32017-76-8 (+/-)-2-(4-bromophenyl)oxirane 
• 586-76-5 4-Bromobenzoic acid 

Downstream Products

• 59824-91-8 2-bromo-1-(4-bromophenyl)-3-phenyl-1-propanone 
• 113530-93-1 2-Benzyl-3-(4-bromo-phenyl)-1,2-dihydro-quinoxaline 
• 742698-54-0 4-(1,1-dimethyl-3-phenyl-propyl)-bromobenzene 
• 43008-85-1 1-(4-bromophenyl)-3-phenylpropane 
• 72758-69-1 (E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one 
• 66648-21-3 3-(p-bromophenyl)indene 

Relevant articles and documents

Nickel-catalyzed α-alkylation of ketones with benzyl alcohols

We reported an efficient method for α-alkylation of ketones with benzyl alcohols using the pyridine-bridged pincer-type N-heterocyclic carbenes nickel complexes as catalysts. A wide range of ketones and benzyl alcohols were efficiently converted into various alkylated products in moderate to high yields. In addition, these nickel complexes were also successfully applied for the synthesis of a wide range of quinoline derivatives.

Iron-catalyzed chemoselective hydride transfer reactions

A Diaminocyclopentadienone iron tricarbonyl complex has been applied in chemoselective hydrogen transfer reductions. This bifunctional iron complex demonstrated a broad applicability in mild conditions in various reactions, such as reduction of aldehydes over ketones, reductive alkylation of various functionalized amines with functionalized aldehydes and reduction of α,β-unsaturated ketones into the corresponding saturated ketones. A broad range of functionalized substrates has been isolated in excellent yields with this practical procedure.

Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols

A new method for converting terminal epoxides and primary alcohols into α-alkylated ketones under borrowing hydrogen conditions is reported. The procedure involves a one-pot epoxide ring opening and alkylation via primary alcohols in the presence of an N-heterocyclic carbene iridium(I) catalyst, under aerobic conditions, with water as the side product.