166904-10-5

Basic information

• Product Name: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(3-phenoxyphenyl)-
• CAS NO: 166904-10-5
• Molecular Formula: C21H16O3
• Molecular Weight: 316.356
• Mol File: 166904-10-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(3-phenoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(3-phenoxyphenyl)-(166904-10-5)
• EPA Substance Registry System: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(3-phenoxyphenyl)-(166904-10-5)

Safety Data

• Hazardous Substances Data: 166904-10-5(Hazardous Substances Data)

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 39515-51-0 3-Phenoxybenzaldehyde 

Downstream Products

• 1339882-56-2 2-(3-phenoxyphenyl)-4H-1-benzopyran-4-one 

Relevant articles and documents

Ionic liquid mediated Cu-catalyzed cascade oxa-Michael-oxidation: Efficient synthesis of flavones under mild reaction conditions

Flavonoids are a class of natural products, found in a wide range of vascular plants and dietary components. Their low toxicity and extensive biological activities, including anti-cancer and anti-bacterial, have made them attractive candidates to serve as therapeutic agents for many diseases. Herein, we disclose a highly efficient synthetic method of CuI-catalyzed cascade oxa-Michael-oxidation, using chalcones as substrates, mediated by the ionic liquid [bmim][NTf2] at a low temperature. This efficient synthetic method has demonstrated high synthetic utility and can afford flavones in good to high yields (up to 98%).