166984-63-0 Usage
Uses
Used in Genetic and Molecular Biology Research:
1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE is used as a key compound in the synthesis of oligonucleotides for genetic and molecular biology research. Its incorporation allows for the creation of modified nucleosides and oligonucleotide analogs, which are crucial for studying various biological processes and understanding the mechanisms of genetic information.
Used in Anticancer Drug Development:
In the pharmaceutical industry, 1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE is used as a building block for designing DNA interstrand cross-links, which have potential applications as anticancer agents. The nitropyrrole group present in the compound enables the development of novel therapeutic strategies against cancer by targeting and disrupting the DNA structure of cancer cells.
Used in Chemical Synthesis of Nucleic Acids:
1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE is used as an essential component in the chemical synthesis of nucleic acids, such as DNA and RNA. The 2-deoxyribofuranosyl group in the compound plays a significant role in constructing the backbone of these nucleic acids, which are vital for various cellular processes, including replication, transcription, and translation.
Used in the Development of Modified Nucleosides:
In the field of biochemistry, 1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE is used as a precursor for the development of modified nucleosides. These modified nucleosides have potential applications in the study of molecular interactions, the development of new drugs, and the understanding of genetic mutations and their effects on cellular function.
Check Digit Verification of cas no
The CAS Registry Mumber 166984-63-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,9,8 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 166984-63:
(8*1)+(7*6)+(6*6)+(5*9)+(4*8)+(3*4)+(2*6)+(1*3)=190
190 % 10 = 0
So 166984-63-0 is a valid CAS Registry Number.
166984-63-0Relevant articles and documents
Synthesis, structure, and deoxyribonucleic acid sequencing with a universal nucleoside: 1-(2′-deoxy-β-D-ribofuranosyl)-3-nitropyrrole
Bergstrom, Donald E.,Zhang, Peiming,Toma, Pascal H.,Andrews, Philip C.,Nichols, Ruthann
, p. 1201 - 1209 (2007/10/02)
A nucleoside analogue, 1-(2′-deoxy-β-D-ribofuranosyl)-3-nitropyrrole (4) was designed to function as a universal replacement for any of the natural nucleosides in DNA sequences. Compound 4 was synthesized by the reaction of 3-nitropyrrole with sodium hydr
