16742-49-7

Basic information

• Product Name: METHYL 2-HYDROXYEICOSANOATE
• Synonyms: DL-ALPHA-HYDROXYARACHIDIC ACID METHYL ESTER;METHYL 2-HYDROXYEICOSANOATE;2-HYDROXY C20:0 METHYL ESTER;dl-A-hydroxyarachidic acid methyl ester;dl-α-hydroxyarachidic acid methyl ester;methyl 2-hydroxyarachidate;2-Hydroxyeicosanoic acid methyl ester;DL-α-Hydroxyarachidic acid methyl ester, Methyl 2-hydroxyeicosanoate
• CAS NO: 16742-49-7
• Molecular Formula: C₂₁H₄₂O₃
• Molecular Weight: 342.56
• Mol File: 16742-49-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 378.6°C at 760 mmHg
• Flash Point: 173.5°C
• Appearance: /
• Density: 0.909g/cm³
• Vapor Pressure: 2.75E-07mmHg at 25°C
• Refractive Index: 1.457
• Storage Temp.: 2-8°C
• PKA: 13.03±0.20(Predicted)
• CAS DataBase Reference: METHYL 2-HYDROXYEICOSANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-HYDROXYEICOSANOATE(16742-49-7)
• EPA Substance Registry System: METHYL 2-HYDROXYEICOSANOATE(16742-49-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 16742-49-7(Hazardous Substances Data)

Usage

General Description

Methyl 2-hydroxyeicosanoate is a chemical compound with the molecular formula C22H44O3. It is classified as a fatty acid ester, specifically a methyl ester of 2-hydroxyeicosanoic acid. This chemical is commonly found in various natural sources, such as plants and animals. Methyl 2-hydroxyeicosanoate has been studied for its potential pharmaceutical and industrial applications, particularly in the fields of cosmetics, pharmaceuticals, and biotechnology. It is also being investigated for its potential use in the development of new drugs and therapeutic agents due to its unique chemical properties and biological activities.

InChI:InChI=1/C21H42O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(22)21(23)24-2/h20,22H,3-19H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 16742-48-6 alpha-hydroxyeicosanoic acid 
• 186581-53-3 diazomethane 
• 93643-04-0 C₂₂H₄₄O₃ 
• 1598425-87-6 1-O-β-D-glucopyranosyl-(2S,3S,4R,9E)-2-[(2'R)-2'-hydroxyeicosanoylamino]-9-tetradecene-1,3,4-triol 

Downstream Products

• 120977-30-2 C₂₈H₄₁F₅O₄ 

Relevant articles and documents

New sphingolipids from Abutilon pakistanicum

Pakistamides A and B (1 and 2, respectively), two new sphingolipids, have been isolated from the AcOEt-soluble sub-fraction of the MeOH extract of the whole plant of Abutilon pakistanicum. Their structures were assigned by 1 H and 13C NMR spectra, and by DEPT and COSY, NOESY, HMQC, HMBC, EI-MS, and FAB-MS experiments.

Spiraeamide, new sphingolipid from Spiraea brahuica

Spiraeamide (1), a new sphingolipid, has been isolated from the ethyl acetate-soluble fraction of the methanolic extract of the whole plant of Spiraea brahuica, along with marrubiin (2), 19-acetylmarrubenol (3), and 6-acetylmarruenol (4). Their structures were elucidated by 1H and 13C NMR spectra, and COSY, NOESY, HMQC, HMBC, EI-MS, and FAB-MS experiments.

Isolation, structure elucidation, total synthesis, and evaluation of new natural and synthetic ceramides on human SK-MEL-1 melanoma cells

Two new long-chain ceramides, trametenamides A (1) and B (2), were isolated from the methanolic extract of the fruiting body of the fungus Trametes menziesii. The structures were elucidated by spectroscopic analyses and chemical transformations, and the absolute stereochemistry of trametenamide B (2) was determined by stereoselective total synthesis of four possible diastereomers. The acetyl derivative of the natural ceramide (1a) and synthetic ceramides (24-27) showed cytotoxicity on the human melanoma cell line SK-MEL-1, which was caused by induction of apoptosis as determined by DNA fragmentation, poly-(ADP-ribose) polymerase cleavage, and procaspase-9 and -8 processing.