16750-99-5 Usage
Description
GERANYL MONOPHOSPHATE, also known as Geranyl pyrophosphate (GPP), is an important intermediate in the biosynthesis of monoterpenes, diterpenes, and tetraterpenes. It is a key precursor in the formation of a wide variety of natural products, including essential oils, hormones, and pigments. Its structure consists of a geranyl group attached to a phosphate group, and it is synthesized in the mevalonate pathway, serving as the substrate for various enzymes involved in terpene biosynthesis. Due to its role in plant metabolism and its potential applications in the production of pharmaceuticals and other valuable compounds, GPP is a significant molecule in the field of natural product chemistry and biotechnology.
Uses
Used in Pharmaceutical Industry:
GERANYL MONOPHOSPHATE is used as a key intermediate for the biosynthesis of various pharmaceutical compounds, due to its role in the formation of monoterpenes, diterpenes, and tetraterpenes.
Used in Aromatherapy Industry:
GERANYL MONOPHOSPHATE is used as a precursor for the production of essential oils, which are widely used in aromatherapy for their therapeutic properties.
Used in Cosmetics Industry:
GERANYL MONOPHOSPHATE is used as a component in the synthesis of fragrances and other scented compounds for use in cosmetics and personal care products.
Used in Agriculture:
GERANYL MONOPHOSPHATE is used in the production of natural plant hormones and growth regulators, which can enhance crop yield and improve plant health.
Used in Biotechnology:
GERANYL MONOPHOSPHATE is used as a substrate for various enzymes involved in terpene biosynthesis, enabling the development of novel biotechnological applications for the production of valuable compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 16750-99-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,5 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16750-99:
(7*1)+(6*6)+(5*7)+(4*5)+(3*0)+(2*9)+(1*9)=125
125 % 10 = 5
So 16750-99-5 is a valid CAS Registry Number.
16750-99-5Relevant articles and documents
Probing the Substrate Promiscuity of Isopentenyl Phosphate Kinase as a Platform for Hemiterpene Analogue Production
Lund, Sean,Courtney, Taylor,Williams, Gavin J.
, p. 2217 - 2221 (2019/08/02)
Isoprenoids are a large class of natural products with wide-ranging applications. Synthetic biology approaches to the manufacture of isoprenoids and their new-to-nature derivatives are limited due to the provision in nature of just two hemiterpene buildin
Enzymatic synthesis of lipid II and analogues
Huang, Lin-Ya,Huang, Shih-Hsien,Chang, Ya-Chih,Cheng, Wei-Chieh,Cheng, Ting-Jen R.,Wong, Chi-Huey
supporting information, p. 8060 - 8065 (2014/08/18)
The emergence of antibiotic resistance has prompted active research in the development of antibiotics with new modes of action. Among all essential bacterial proteins, transglycosylase polymerizes lipid II into peptidoglycan and is one of the most favorable targets because of its vital role in peptidoglycan synthesis. Described in this study is a practical enzymatic method for the synthesis of lipid II, coupled with cofactor regeneration, to give the product in a 50-70 % yield. This development depends on two key steps: the overexpression of MraY for the synthesis of lipid I and the use of undecaprenol kinase for the preparation of polyprenol phosphates. This method was further applied to the synthesis of lipid II analogues. It was found that MraY and undecaprenol kinase can accept a wide range of lipids containing various lengths and configurations. The activity of lipid II analogues for bacterial transglycolase was also evaluated.
