167693-61-0

Basic information

• Product Name: Oxazole, 4,5-dihydro-4-(2-methylpropyl)-2-phenyl-, (4S)-
• Synonyms: (S)-2-phenyl-4-isobutyl-oxazoline;(4S)-2-phenyl-4-isobutyl-2-oxazoline;Oxazole,4,5-dihydro-4-(2-methylpropyl)-2-phenyl-,(4S);(-)-(4S)-4,5-Dihydro-4-isobutyl-2-phenyloxazole;(S)-4-isobutyl-2-phenyl-4,5-dihydrooxazole;(4S)-4-isobutyl-2-phenyl-2-oxazoline
• CAS NO: 167693-61-0
• Molecular Formula: C13H17NO
• Molecular Weight: 203.284
• Mol File: 167693-61-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 302.5±11.0 °C(Predicted)
• Density: 1.04±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Oxazole, 4,5-dihydro-4-(2-methylpropyl)-2-phenyl-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 4,5-dihydro-4-(2-methylpropyl)-2-phenyl-, (4S)-(167693-61-0)
• EPA Substance Registry System: Oxazole, 4,5-dihydro-4-(2-methylpropyl)-2-phenyl-, (4S)-(167693-61-0)

Safety Data

• Hazardous Substances Data: 167693-61-0(Hazardous Substances Data)

Upstream product

• 7533-40-6 (S)-2-amino-4-methylpentan-1-ol 
• 5333-86-8 ethyl benzimidate hydrochloride 
• 614-16-4 Benzoylacetonitrile 
• 100-52-7 benzaldehyde 
• 257296-58-5 N-((S)-1-hydroxymethyl-3-methyl-butyl)-benzamide 
• 3389-54-6 n-benzoylpyrrolidine 
• 928150-62-3 N-(α,α-difluorobenzyl)pyrrolidine 
• 100-47-0 benzonitrile 

Downstream Products

• 167693-62-1 (-)-(4S)-4,5-Dihydro-2-<2'-(diphenylphosphino)phenyl>-4-isobutyloxazole 

Relevant articles and documents

Efficient one-pot synthesis of 2-oxazolines from benzoylacetonitrile and β-aminoalcohols mediated by ZnCl2

A series of 2-oxazolines were synthesized using a simple, one-pot method under inert, moisture-free conditions from the benzoylacetonitrile and β-aminoalcohols mediated by 115-172 mol% ZnCl2. Structures of products were fully characterized by NMR, IR and MS. [Figure not available: see fulltext.]

Synthesis of 2-oxazolines and related N-containing heterocycles using [Et2NSF2]BF4 as a cyclodehydration agent

The preparation of 2-oxazolines and related N-containing heterocycles from the corresponding hydroxyamides using XtalFluor-E ([Et2NSF 2s]BF4) as a cyclodehydration agent is described. A wide range of heterocycles are obtai

METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE

The present invention is a method for producing a 2-oxazoline analogue or a 1,3-oxazine analogue represented by the following general formula (3) by reacting a 1,2-aminoalcohol compound or a 1,2-aminothiol compound with an α,α-dihaloamine compound. (In the formula, n represents 0 or 1, and R represents an oxygen atom or a sulfur atom. R1, R2 and R3 each represents an atom or a group shown in Group 1 to Group 3, and R° represents an atom or a group shown in Group 2 or Group 3. Two or more of R1, R2 and R3 may be bonded to each other to form a ring. Group 1: a hydrogen atom, a halogen atom, a nitro group, a cyano group, a formyl group, a carboxyl group, a sulfonyl group, a sulfinoyl group or a sulfenyl group; Group 2: an alkyl group, which may have an arbitrary substituent, an aryl group or an aralkyl group; and Group 3: an alkyl-substituted, aryl-substituted or aralkyl-substituted oxy group, a carbonyl group, an oxycarbonyl group, a carbonyloxy group, a thio group, a sulfonyl group, a sulfinoyl group or a sulfenyl group)