1677-29-8

Basic information

• Product Name: N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE
• Synonyms: N,N'-bis(4-fluorophenyl)propanediamide;N1,N1-Bis(4-fluorophenyl)MalonaMide;PropanediaMide,N1,N3-bis(4-fluorophenyl)-
• CAS NO: 1677-29-8
• Molecular Formula: C₁₅H₁₂F₂N₂O₂
• Molecular Weight: 290.268
• Mol File: 1677-29-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 549.3°Cat760mmHg
• Flash Point: 286°C
• Appearance: /
• Density: 1.392g/cm³
• CAS DataBase Reference: N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE(1677-29-8)
• EPA Substance Registry System: N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE(1677-29-8)

Safety Data

• Hazardous Substances Data: 1677-29-8(Hazardous Substances Data)

Usage

Description

N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE is a chemical compound characterized by its molecular formula C17H14F2N2O2. It features a malonamide backbone with two 4-fluoro-phenyl groups attached, which enables it to engage in complex formation with metal ions and other molecules. N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE is particularly recognized for its capacity to form stable complexes with a variety of metal cations, a property that extends its utility across several fields.

Uses

Used in Coordination Chemistry:
N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE serves as a ligand in coordination chemistry, facilitating the formation of complexes with metal ions. Its structural design allows for versatile interactions, making it a valuable component in the synthesis of new coordination compounds.
Used in Catalysis:
The ability of N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE to form stable complexes with metal cations positions it as a potential catalyst or catalyst precursor in various chemical reactions. Its use can enhance the efficiency and selectivity of catalytic processes.
Used in Extraction and Separation Processes:
In the realm of extraction and separation techniques, N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE can be utilized to selectively bind with certain metal ions. This selective binding property is advantageous for processes that require the separation or purification of metal-containing compounds.
Used in Pharmaceutical Applications:
Given its complex-forming capabilities, N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE holds potential in the pharmaceutical industry. It may be employed in the development of new drugs or as a component in drug delivery systems, targeting specific metal ion interactions relevant to therapeutic effects.
Used in Materials Science:
N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE's interaction with metal ions can also be leveraged in materials science to create new materials with tailored properties. This could include the development of advanced catalysts, sensors, or materials with specific electronic or optical characteristics.
Used in Environmental Remediation:
N,N''-BIS-(4-FLUORO-PHENYL)-MALONAMIDE's metal-binding properties can be applied in environmental remediation efforts, particularly for the treatment of water or soil contaminated with heavy metals. Its use could facilitate the extraction and removal of these contaminants, aiding in the cleanup of polluted environments.

Upstream product

• 371-40-4 4-fluoroaniline 
• 105-53-3 diethyl malonate 
• 108-59-8 malonic acid dimethyl ester 

Downstream Products

• 1677-37-8 6-fluoro-4-hydroxy-1H-quinolin-2-one 
• 1614221-71-4 3,3-dibenzyl-6-fluoro-4-hydroxy-3,4-dihydro-1H-quinolin-2-one 
• 1614221-49-6 3,3-dibenzyl-6-fluoro-1H-quinoline-2,4-dione 
• 1309870-85-6 C₁₅H₉FIN₃O₂ 
• 1309870-84-5 C₁₆H₉F₄N₃O₂ 
• 1309870-83-4 C₁₅H₉ClFN₃O₂ 
• 1309870-81-2 C₁₅H₉BrFN₃O₂ 
• 1309870-80-1 C₁₅H₉ClFN₃O₂ 
• 1234896-95-7 C₁₅H₉FN₄O₄ 
• 1234896-94-6 C₁₆H₉FN₄O₂ 

Relevant articles and documents

Synthesis of symmetrically substituted 3,3-dibenzyl-4-hydroxy-3,4-dihydro- 1H-quinolin-2-ones, as novel quinoline derivatives with antibacterial activity

A novel series of symmetrically substituted 3,3-dibenzyl-4-hydroxy-3,4- dihydro-1H-quinolin-2-ones was synthesized and tested as antimicrobials. The minimum inhibitory concentration (MIC) values of the most active heterocycles were slightly higher than those exhibited by levofloxacin, employed as comparator. Structural factors affecting the activity were explored along three diversification points, including the substituents of the aromatic rings of the 3-benzyl moieties, as well as the functionalization of both, the homocyclic ring of the heterocycle and the quinolonic nitrogen atom. 6-Chloro and 3,3-bis(4′-chlorobenzyl) derivatives showed the lower MIC values. Optimally substituted heterocycles were synthesized, which exhibited enhanced activity.

Synthesis of 6-chloro and 6-fluoro-4-hydroxyl-2-quinolone and their azo disperse dyes

In this study, 6-chloro-4-hydroxy-2-quinolone and 6-flouro-4-hydroxy-2-quinolone were synthesized from corresponding dianilides. These compounds were coupled with some diazotized aromatic amines to give the corresponding azo disperse dyes. The structures