16782-08-4

Basic information

• Product Name: P-HYDROXYBENZOIC ACID POTASSIUM SALT
• Synonyms: P-HYDROXYBENZOIC ACID POTASSIUM SALT;POTASSIUM P-HYDROXYBENZOATE;POTASSIUM 4-HYDROXYBENZOATE;4-HYDROXYBENZOIC ACID MONOPOTASSIUM SALT;Benzoicacid,4-hydroxy-,monopotassiumsalt;POTASSIUM PARABEN;Einecs 240-830-2
• CAS NO: 16782-08-4
• Molecular Formula: C₇H₅O₃*K
• Molecular Weight: 176.21
• EINECS: 240-830-2
• Product Categories: Aromatic Esters;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 16782-08-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 336.2 °C at 760 mmHg
• Flash Point: 171.3 °C
• Appearance: /
• Vapor Pressure: 4.48E-05mmHg at 25°C
• CAS DataBase Reference: P-HYDROXYBENZOIC ACID POTASSIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: P-HYDROXYBENZOIC ACID POTASSIUM SALT(16782-08-4)
• EPA Substance Registry System: P-HYDROXYBENZOIC ACID POTASSIUM SALT(16782-08-4)

Safety Data

• Hazardous Substances Data: 16782-08-4(Hazardous Substances Data)

Usage

General Description

P-hydroxybenzoic acid potassium salt is a white crystalline powder that is commonly used as a food preservative and additive. It is the potassium salt of p-hydroxybenzoic acid, also known as paraben. P-HYDROXYBENZOIC ACID POTASSIUM SALT has antimicrobial properties and is effective in preventing the growth of bacteria and fungi in various products, including food, cosmetics, and pharmaceuticals. It is often added to products such as sauces, jams, syrups, and beverages to extend their shelf life and maintain their quality. P-hydroxybenzoic acid potassium salt is approved for use in food and cosmetic products by regulatory agencies but should be used with caution as high doses have been associated with potential health risks.

InChI:InChI=1/C7H6O3.K/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

Upstream product

• 124-38-9 carbon dioxide 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 123-08-0 4-hydroxy-benzaldehyde 
• 16435-03-3 4-((2-phenylhydrazono)methyl)phenol 
• 99-96-7 4-hydroxy-benzoic acid 

Downstream Products

• 619-86-3 4-(ethoxy)benzoic acid 
• 15872-41-0 4-(pentyloxy)benzoic acid 
• 2493-84-7 p-octyloxybenzoic acid 
• 61482-49-3 4-hydroxy-benzoic acid ; hexadecyl-trimethyl-ammonium salt 
• 1360144-76-8 (5-methoxy-4-oxo-4H-pyran-2-yl)methyl 4-hydroxybenzoate 
• 99-96-7 4-hydroxy-benzoic acid 
• 2312-15-4 p-dodecyloxybenzoic acid 
• 5438-19-7 4-propoxybenzoic acid 
• 141339-57-3 4-Hydroxybenzoesaeure-2-oxoheptylester 
• 15872-43-2 4-nonyloxybenzoic acid 
• 1142-39-8 para-hexyloxybenzoic acid 
• 15872-42-1 4-heptyloxybenzoic acid 
• 100-09-4 4-methoxybenzoic acid 
• 15872-44-3 4-(n-undecyloxy)benzoic acid 

Relevant articles and documents

An Anionic, Chelating C(sp3)/NHC ligand from the Combination of an N-heterobicyclic Carbene and Barbituric Heterocycle

The coordination chemistry of the anionic NHC1-based on an imidazo[1,5-a]pyridin-3-ylidene (IPy) platform substituted at the C5 position by an anionic barbituric heterocycle was studied with d6(Ru(II), Mn(I)) and d8(Pd(II), Rh(I), Ir(I), Au(III)) transition-metal centers. While the anionic barbituric heterocycle is planar in the zwitterionic NHC precursor 1·H, NMR spectroscopic analyses supplemented by X-ray diffraction studies evidenced the chelating behavior of ligand 1-through the carbenic and the malonic carbon atoms in all of the complexes, resulting from a deformation of the lateral barbituric heterocycle. The complexes were obtained by reaction of the free carbene with the appropriate metal precursor, except for the Au(III) complex 10, which was obtained by oxidation of the antecedent gold(I) complex [AuCl(1)]?with PhICl2as an external oxidant. During the course of the process, the kinetic gold(I) intermediate 9 resulting from the oxidation of the malonic carbon of the barbituric moiety was isolated upon crystallization from the reaction mixture. The νCOstretching frequencies recorded for complex [Rh(1)(CO)2] (5) demonstrated the strong donating character of the malonate-C(sp3)/NHC ligand 1-. The ruthenium complex [Ru(1)Cl(p-cymene)] (11) was implemented as a precatalyst in the dehydrogenative synthesis of carboxylic acid derivatives from primary alcohols and exhibited high activities at low catalyst loadings (25-250 ppm) and a large tolerance toward functional groups.

4-HYDROXY BENZOATE DERIVATIVES FOR USE IN THE TREATMENT OF INFECTION, INFLAMMATION OR PAIN

The invention provides a compound of the general formula (I) for use in the topical treatment of infection, inflammation and/or pain: wherein R1 independently represents a methylene group, an ethylene group or a straight or branched chain C3 to C6 alkylene group; R2 independently represents a hydrogen atom, a methyl group, an ethyl group or a straight or branched chain C3 to C20 alkyl group; x represents 0 or an integer from 1 to 4 and y represents 0 or an integer from 1 to 4, wherein the sum of x and y is 4; and Z represents a hydrogen atom or (HOR1)yR2XN⊕; compositions comprising the compound; use of the compound in the manufacture of a medicament; and methods of medical treatment comprising the topical application of the compound.