167938-56-9 Usage
Description
N-BOC-(S)-1-AMINO-2-PROPANOL, also known as (S)-1-(Boc-amino)-2-propanol, is a chiral compound that serves as a pharmaceutical intermediate. It is characterized by its clear and colorless liquid form, which is essential for various chemical reactions and synthesis processes in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
N-BOC-(S)-1-AMINO-2-PROPANOL is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its chiral nature and clear, colorless liquid form make it a valuable component in the development of enantiomerically pure compounds, which are crucial for the efficacy and safety of many pharmaceutical products.
As a pharmaceutical intermediate, N-BOC-(S)-1-AMINO-2-PROPANOL plays a critical role in the synthesis of various drug molecules, contributing to the advancement of medical treatments and therapies. Its unique chemical properties allow for targeted drug development, ensuring that the final products are both effective and safe for use in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 167938-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,9,3 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 167938-56:
(8*1)+(7*6)+(6*7)+(5*9)+(4*3)+(3*8)+(2*5)+(1*6)=189
189 % 10 = 9
So 167938-56-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H17NO3/c1-6(10)5-9-7(11)12-8(2,3)4/h6,10H,5H2,1-4H3,(H,9,11)/t6-/m0/s1
167938-56-9Relevant articles and documents
Asymmetric catalytic synthesis of enantiopure N-protected 1,2-amino alcohols
Bartoli, Giuseppe,Bosco, Marcella,Carlone, Armando,Locatelli, Manuela,Melchiorre, Paolo,Sambri, Letizia
, p. 3973 - 3975 (2004)
(Chemical Equation Presented) The asymmetric aminolytic kinetic resolution (AKR) of racemic terminal epoxides using carbamates as the nucleophile catalyzed by (salen)CoIII complex provides a practical and straightforward method for the synthesis of both aliphatic and aromatic N-Boc- or N-Cbz-protected 1,2-amino alcohols in almost enantiomerically pure form (ee ≥ 99%). The AKR uses an easily accessible catalyst and inexpensive starting materials, and the reactions are conveniently carried out at room temperature under an air atmosphere.