168143-68-8Relevant articles and documents
A second-generation 99mtechnetium single photon emission computed tomography agent that provides in vivo images of the dopamine transporter in primate brain
Meltzer, Peter C.,Blundell, Paul,Zona, Thomas,Yang, Lihua,Huang, Hong,Bonab, Ali A.,Livni, Eli,Fischman, Alan,Madras, Bertha K.
, p. 3483 - 3496 (2007/10/03)
The dopamine transporter (DAT), located presynaptically on dopamine neurons, provides a marker for Parkinson's disease (Pd) and attention deficit hyperactivity disorder (ADHD). In ADHD, DAT density levels are elevated, while in Pd these levels are deplete
Synthesis of the 2β,3α- and 2β,3β-Isomers of 3-(p-substituted phenyl)tropane-2-carboxylic Acid Methyl Esters
Keverline, Kathryn I.,Abraham, Philip,Lewin, Anita H.,Carroll, F. Ivy
, p. 3099 - 3102 (2007/10/02)
The synthesis of 3-(p-substituted phenyl)trop-2-ene-2-carboxylic acid methyl ester 8 and its reduction with samarium iodide provide a new synthesis of 3β-(4'-substituted phenyl)tropane-2β-carboxylic acid methyl ester (2) and, in addition, give the first s