168157-23-1Relevant articles and documents
Nonpeptide GPIIb/IIIa inhibitors. 16. Thieno[2,3-b]thiophene α-sulfonamides are potent inhibitors of platelet aggregation
Prugh, John D.,Gould, Robert J.,Lynch, Robert J.,Zhang, Guixiang,Cook, Jacquelynn J.,Holahan, Marie A.,Stranieri, Maria T.,Sitko, Gary R.,Gaul, S. Lee,Bednar, Rodney A.,Bednar, Bohumil,Hartman, George D.
, p. 865 - 870 (1997)
Centrally constrained thieno[2,3-b]thiophene sulfonamides have provided a potent, selective, orally active series of platelet aggregation inhibitors. Compound 21 showed excellent activity in the dog after a single oral dose of 200 μg/kg.