16825-78-8Relevant articles and documents
NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS
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Page/Page column 10, (2010/04/03)
Iodylbenzene derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are used as precursors in aromatic nucleophilic substitution reactions. The iodyl group (IO2) is regiospecifically substituted by nucleophilic fluoride to provide the corresponding fluoroaryl derivatives. No-carrier-added [F-18] fluoride ion derived from anhydrous [F- 18]KF/Kryptofix, [F-18]CsF or a quaternary ammonium fluoride (e.g., Me4NF, Et4NF, n-Bu4NF, (PhCH2)4NF) exclusively substitutes the iodyl moiety in these derivatives and provides high specific activity F- 18 labeled fluoroaryl analogs. Iodyl derivatives of a benzothiazole analog and 6-iodyl-L-dopa derivatives have been synthesized as precursors and have been used in the preparation of no-carrier-added [F-18]fluorobenzothiazole as well as 6-[F-18]fluoro-L-dopa.
Use of Potassium Bromate: Syntheses of Iodoxybenzene Derivatives
Banaerjee, Amalendu,Banerjee, Gopal Chandra,Bhattacharya, Sudin,Banerjee, Santa,Samaddar, Haraprasad
, p. 605 - 607 (2007/10/02)
Synthesis of iodoxy compounds by the oxidation of various iodobenzene derivatives using potassium bromate under acidic condition have been discussed.