16834-21-2Relevant articles and documents
Silica-supported pyrrolidine-triazole, an insoluble, recyclable organocatalyst for the enantioselective Michael addition of ketones to nitroalkenes
Zhao, Ya-Bin,Zhang, Lin-Wei,Wu, Lu-Yong,Zhong, Xing,Li, Rong,Ma, Jian-Tai
, p. 1352 - 1355 (2008)
A highly efficient, silica-supported organocatalyst for the Michael addition of ketones to nitroalkenes is successfully developed. A 1,2,3-triazole ring, constructed via a click 1,3-dipolar cycloaddition, plays a dual role of grafting the chiral pyrrolidi
Prolinal dithioacetals: Highly efficient organocatalysts for the direct nitro-Michael additions in both organic and aqueous media
Mandal, Tanmay,Kuo, Wen,Su, Matthew,Bhowmick, Kartick,Zhao, John C.-G.
, p. 6597 - 6603 (2017/10/18)
Some novel prolinal dithioacetal derivatives have been synthesized and applied as the organocatalysts for the direct Michael addition of ketones and aldehydes to nitroalkenes. High enantioselectivities and diastereoselectivities have been obtained in both
Synthesis of chiral γ - nitrophenol compound method (by machine translation)
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Paragraph 0138-0140, (2017/09/01)
The invention provides a method for synthesizing chiral γ - nitrophenol compound method, said method comprising the following steps: the chiral catalyst, cocatalyst, organic solvent A mixing, stirring condition point pen (iii) ketone compound shown in formula (iv) indicated by the nitroolefin compound, for 10 - 40 °C stirring for 6 - 18 the H, formula (v) compound of formula; to the of formula (v) is added in the compounds of the copper bromide, in an organic solvent in the B, in the 90 - 120 °C stirring reaction under 0.8 h - 6 h, formula (i) shown γ - nitrophenol compound of; the advantage of this invention is characterized in that: the chiral nitro alkanes substituted phenol compound has wide application space, synthetic method of this invention, the operation is simple, mild reaction conditions, show good response characteristic, the reaction yield is high, good selectivity. (by machine translation)