16844-27-2 Usage
Description
TOLUENE-4-SULFINIC ACID LITHIUM SALT, also known as lithium p-toluenesulfinate, is a chemical compound derived from toluene-4-sulfonic acid. It is a versatile reagent in organic synthesis and possesses unique properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
TOLUENE-4-SULFINIC ACID LITHIUM SALT is used as a synthetic reagent for the preparation of 2-oxo-1,3-diphenyl-1,2-dihydroquinoline-4-carbonitrile, which is an important intermediate in the synthesis of various pharmaceutical compounds. Its use in this application is due to its ability to facilitate the formation of complex molecular structures.
Used in Chemical Research:
In the field of chemical research, TOLUENE-4-SULFINIC ACID LITHIUM SALT is used as a synthetic reagent for the preparation of highly fluorescent compounds, such as 3-amino-6-methoxy-4-p-tolylsulfonylquinolone. This application takes advantage of its unique chemical properties to create novel fluorescent molecules with potential uses in various industries, including biotechnology and materials science.
Used in Material Science:
TOLUENE-4-SULFINIC ACID LITHIUM SALT can be employed in the development of new materials with specific properties, such as the highly fluorescent compound mentioned above. Its use in this industry is driven by the need for innovative materials with unique characteristics for various applications, including sensors, displays, and imaging technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 16844-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,4 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16844-27:
(7*1)+(6*6)+(5*8)+(4*4)+(3*4)+(2*2)+(1*7)=122
122 % 10 = 2
So 16844-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H8O2S.Li/c1-6-2-4-7(5-3-6)10(8)9;/h2-5H,1H3,(H,8,9);/q;+1/p-1
16844-27-2Relevant articles and documents
Copper-Catalyzed Remote C?H Functionalization of 8-Aminoquinolines with Sodium and Lithium Sulfinates
Liang, Shuai,Manolikakes, Georg
, p. 2371 - 2378 (2016)
A simple and mild copper-catalyzed sulfonylation of 8-aminoquinolines with sodium and lithium sulfinates is reported. In the presence of manganese(III) acetate [Mn(OAc)3] as cooxidant a highly site-selective C?H functionalization at the C-5 position takes place. The reaction proceeds readily at room temperature in air and various sulfones were synthesized in moderate to high yields. Moreover, a straightforward procedure for the conversion of organolithium reagents and sulfur dioxide into C-5 sulfonylated quinolines was developed. (Figure presented.).
Moser et al.
, p. 770 (1967)
Manganese(III) Acetate Mediated C–H Sulfonylation of 1,4-Dimethoxybenzenes with Sodium and Lithium Sulfinates
Liang, Shuai,Ren, Yueling,Manolikakes, Georg
supporting information, p. 4117 - 4120 (2017/08/07)
A simple and mild Mn(OAc)3-promoted oxidative coupling of 1,4-dimethoxybenzenes with sodium and lithium sulfinates was developed. The reaction proceeded readily at room temperature in air, and various sulfones were synthesized in moderate to high yields. In addition, a straightforward approach for the conversion of organolithium reagents and sulfur dioxide into sulfonylated 1,4-dimethoxybenzenes was explored.
