168466-85-1 Usage
Description
(S)-1-Benzyl-3-aminopiperidine, also known as (S)-3-Amino-1-benzylpiperidine, is a white solid organic compound that serves as a crucial intermediate in various chemical syntheses. It is characterized by its unique molecular structure, which contributes to its diverse applications across different industries.
Uses
Used in Organic Synthesis:
(S)-1-Benzyl-3-aminopiperidine is used as a key intermediate in organic synthesis for the development of new compounds and materials. Its versatile chemical properties allow it to be a valuable building block in creating a wide range of products.
Used in Pharmaceutical Industry:
(S)-1-Benzyl-3-aminopiperidine is used as an important raw material in the pharmaceutical industry for the synthesis of various drugs. Its unique structure makes it a promising candidate for the development of new medications with potential therapeutic applications.
Used in Agrochemicals:
In the agrochemical industry, (S)-1-Benzyl-3-aminopiperidine is utilized as a vital intermediate for the production of pesticides, herbicides, and other agricultural chemicals. Its role in these applications is crucial for enhancing crop protection and yield.
Used in Dyestuff:
(S)-1-Benzyl-3-aminopiperidine is also employed in the dyestuff industry as a key intermediate for the synthesis of various dyes and pigments. Its chemical properties enable the creation of a diverse range of colorants used in different applications, such as textiles, plastics, and printing inks.
Check Digit Verification of cas no
The CAS Registry Mumber 168466-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,4,6 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 168466-85:
(8*1)+(7*6)+(6*8)+(5*4)+(4*6)+(3*6)+(2*8)+(1*5)=181
181 % 10 = 1
So 168466-85-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2/c13-12-7-4-8-14(10-12)9-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10,13H2/t12-/m0/s1
168466-85-1Relevant articles and documents
The identification and use of robust transaminases from a domestic drain metagenome
Leipold, Leona,Dobrijevic, Dragana,Jeffries, Jack W.E.,Bawn, Maria,Moody, Thomas S.,Ward, John M.,Hailes, Helen C.
, p. 75 - 86 (2019/01/11)
Transaminases remain one of the most promising biocatalysts for use in chiral amine synthesis, however their industrial implementation has been hampered by their general instability towards, for example, high amine donor concentrations and organic solvent content. Herein we describe the identification, cloning and screening of 29 novel transaminases from a household drain metagenome. The most promising enzymes were fully characterised and the effects of pH, temperature, amine donor concentration and co-solvent determined. Several enzymes demonstrated good substrate tolerance as well as an unprecedented robustness for a wild-type transaminase. One enzyme in particular readily accepted IPA as an amine donor giving the same conversion with 2-50 equivalents, as well as being tolerant to a number of co-solvents, and operational in up to 50% DMSO-a characteristic as yet unobserved in a wild-type transaminase. This work highlights the value of using metagenomics for biocatalyst discovery from niche environments, and here has led to the identification of one of the most robust native transaminases described to date, with respect to IPA and DMSO tolerance.
Stereocontrolled dopamine receptor binding and subtype selectivity of clebopride analogues synthesized from aspartic acid
Einsiedel, Juergen,Weber, Klaus,Thomas, Christoph,Lehmann, Thomas,Huebner, Harald,Gmeiner, Peter
, p. 3293 - 3296 (2007/10/03)
Employing the achiral 4-aminopiperidine derivative clebopride as a lead compound, chiral analogues were developed displaying dopamine receptor binding profiles that proved to be strongly dependent on the stereochemistry. Compared to the D1 receptor, the t
