168481-89-8

Basic information

• Product Name: 3,4-bis(2-chlorophenyl)-1,2,5-oxadiazole 2-oxide
• Synonyms: 3,4-bis(2-chlorophenyl)-1,2,5-oxadiazole 2-oxide
• CAS NO: 168481-89-8
• Molecular Weight: 307.136
• Mol File: 168481-89-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3,4-bis(2-chlorophenyl)-1,2,5-oxadiazole 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-bis(2-chlorophenyl)-1,2,5-oxadiazole 2-oxide(168481-89-8)
• EPA Substance Registry System: 3,4-bis(2-chlorophenyl)-1,2,5-oxadiazole 2-oxide(168481-89-8)

Safety Data

• Hazardous Substances Data: 168481-89-8(Hazardous Substances Data)

Upstream product

• 29568-74-9 (Z)-2-chlorobenzaldehyde (α)-chloro-oxime 
• 49660-38-0 2-chlorobenzonitrile oxide 
• 78-94-4 methyl vinyl ketone 
• 3717-26-8 2-chlorobenzaldoxime 
• 3717-28-0 2-chloro benzaldehyde oxime 
• 3717-26-8 (E)-2-chlorobenzaldehyde oxime 
• 7284-07-3 5,6-dideoxy-1,2-O-isopropylidene-α-D-xylo-hex-5-eno-furanose 
• 29568-74-9 2-chloro-N-hydroxybenzimidoyl chloride 

Downstream Products

• 20668-13-7 methyl N-(2-chlorophenyl)carbamate 
• 5293-77-6 1-chloro-2-(2'-chlorophenylethynyl)-benzene 
• 108794-66-7 9,10-(3',3',4',4'-tetramethylcyclobuteno)phenanthrene 
• 3320-83-0 o-chlorophenyl isocyanate 

Relevant articles and documents

Synthesis and Antifungal Activities of Furoxan Derivatives Designed as Novel Fungicide

Furoxan derivatives 3-11 were designed and synthesized as potential fungicides. Symmetrically substituted furoxan derivatives 3a-j were prepared by dimerization of the corresponding nitrile oxide generated from N-hydroxyliminoyl chloride 2 in situ. Further functional group modifications of aldehyde 4, a key intermediate, generated furoxan derivatives 5-11. The fungicidal activities of furoxan derivatives 3-11 were observed over a broad spectrum of plant fungi at 250 ppm.

3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation

3-Aryl-5-hydroxy-5-vinyl-2-isoxazolines were synthesized by reacting aryl nitrile oxides with the lithium enolate of methyl vinyl ketone (MVK) at-78 °C. Fair to good yields are obtained in the case of aryl nitrile oxides bearing electron-withdrawing group