16874-01-4Relevant articles and documents
Suzuki-Miyaura cross-coupling reaction of monohalopyridines and L-aspartic acid derivative
Mikagi, Ayame,Tokairin, Dai,Usuki, Toyonobu
supporting information, p. 4602 - 4605 (2018/11/25)
Suzuki-Miyaura cross-coupling reaction of halogenated pyridines and a borated L-aspartic acid derivative was conducted. The reactivity of chloro-, bromo-, and iodo-pyridines with substituents at the C2, C3, and C4 positions was investigated. Electron dens
Versatile selective α-carboxylic acid esterification of N-protected amino acids and peptides by alcalase
Nuijens, Timo,Cusan, Claudia,Kruijtzer, John A. W.,Rijkers, Dirk T. S.,Liskamp, Rob M. J.,Quaedflieg, Peter J. L. M.
experimental part, p. 809 - 814 (2009/07/11)
Under continuous removal of water, the industrial protease Alcalase allows selective synthesis of α-carboxylic acid methyl, ethyl, benzyl, allyl, 2-(trimethylsilyl)ethyl, and tert-butyl esters of amino acids and peptides under mild conditions in very high
Dicarbonates: Convenient 4-dimethylaminopyridine catalyzed esterification reagents
Takeda,Akiyama,Nakamura,Takizawa,Mizuno,Takayanagi,Harigaya
, p. 1063 - 1066 (2007/10/02)
The DMAP (4-dimethylaminopyridine) catalyzed reaction of dialkyl dicarbonates la-e and carboxylic acids 2 afforded the corresponding esters 5 in good yield.