16879-40-6

Basic information

• Product Name: 4,6-Dimethyl-2-iodopyrimidine
• Synonyms: 2-iodo-4,6-dimethylpyrimidine
• CAS NO: 16879-40-6
• Molecular Formula: C₆H₇IN₂
• Molecular Weight: 234.04
• Product Categories: pharmacetical
• Mol File: 16879-40-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 128-129 °C
• Boiling Point: 305.1°Cat760mmHg
• Flash Point: 138.3°C
• Appearance: /
• Density: 1.793g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.606
• PKA: 0.37±0.30(Predicted)
• CAS DataBase Reference: 4,6-Dimethyl-2-iodopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dimethyl-2-iodopyrimidine(16879-40-6)
• EPA Substance Registry System: 4,6-Dimethyl-2-iodopyrimidine(16879-40-6)

Safety Data

• Hazardous Substances Data: 16879-40-6(Hazardous Substances Data)

Usage

Description

4,6-Dimethyl-2-iodopyrimidine is a chemical compound characterized by the molecular formula C6H7IN2. It is a pyrimidine derivative featuring two methyl groups and an iodine atom, known for its solid state at room temperature and a coloration that ranges from white to yellow. 4,6-Dimethyl-2-iodopyrimidine is notable for its applications in various chemical syntheses and should be handled with caution due to its potential harmful effects if ingested, inhaled, or if it comes into contact with the skin or eyes.

Uses

Used in Pharmaceutical Industry:
4,6-Dimethyl-2-iodopyrimidine serves as a crucial intermediate in the synthesis of various pharmaceuticals. Its unique structure contributes to the development of new drugs, making it an essential component in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-Dimethyl-2-iodopyrimidine is utilized as an intermediate in the production of pesticides and other agrochemicals, highlighting its versatility in chemical synthesis for different applications.
Used in Dye Production:
4,6-Dimethyl-2-iodopyrimidine is also employed in the manufacturing process of dyes, capitalizing on its chemical properties to create a range of colorants used in various industries.
Used in Organic Compounds Synthesis:
Beyond its applications in pharmaceuticals, agrochemicals, and dyes, 4,6-Dimethyl-2-iodopyrimidine is a valuable precursor in the synthesis of other organic compounds, demonstrating its broad utility in organic chemistry.

InChI:InChI=1/C6H7IN2/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3

Upstream product

• 123-54-6 acetylacetone 
• 34289-60-6 4,6-dimethyl-2-hydroxy-pyrimidine hydrochloride 
• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 

Downstream Products

• 1581300-16-4 (E,E)-4,6-bis(4-dimethylaminostyryl)-2-iodopyrimidine 
• 1581300-26-6 N,N-bis(4-iodophenyl)-4-[4-bis(E,E)-{4,6-(dibutylaminostyryl)pyrimidin-2-yl}ethynyl]aniline 
• 1581300-25-5 N,N-bis(4-iodophenyl)-4-[4-bis(E,E)-{4,6-(dimethylaminostyryl)pyrimidin-2-yl}ethynyl]aniline 
• 1581300-22-2 (E,E)-4,6-bis(4-N-dibutylaminostyryl)-2-ethynylpyrimidine 
• 1581300-20-0 (E,E)-4,6-bis(4-dimethylaminostyryl)-2-ethynylpyrimidine 
• 1581300-23-3 C₂₇H₂₈N₂O₂Si 
• 1581300-24-4 (E,E)-4,6-bis(4-methoxystyryl)-2-ethynylpyrimidine 
• 1581300-21-1 C₄₁H₅₈N₄Si 
• 1581300-19-7 C₂₉H₃₄N₄Si 
• 1581300-11-9 tris[4-{2-(4,6-dimethylpyrimidin-2-yl)ethynylpheny}]amine 
• 108-79-2 4,6-dimethyl-2(1H)-pyrimidinone 
• 86520-99-2 2-ethynyl-4,6-dimethylpyrimidine 
• 1488300-30-6 4-({7-[(4,6-dimethylpyrimidin-2-yl)ethynyl]-9,9-dihexyl-9H-fluoren-2-yl}ethynyl)-N,N-dimethylaniline 
• 1488300-13-5 4-[7-(4,6-dimethylpyrimidin-2-yl)-9,9-dihexyl-9H-fluoren-2-yl]-N,N-dimethylaniline 

Relevant articles and documents

Improved synthesis of 2,2′-bipyrimidine

A high-yield synthesis was developed for the preparation of 2,2′-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4′,6,6′-tetramethyl-2,2′-bipyrimidine (2) and 5,5′-dibromo-2,2′-bipyrimidine (3).