168893-04-7

Basic information

• Product Name: 1,4-Dioxaspiro[4.5]decan-8-amine, N,N-bis(phenylmethyl)-
• CAS NO: 168893-04-7
• Molecular Formula: C22H27NO2
• Molecular Weight: 337.462
• Mol File: 168893-04-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,4-Dioxaspiro[4.5]decan-8-amine, N,N-bis(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dioxaspiro[4.5]decan-8-amine, N,N-bis(phenylmethyl)-(168893-04-7)
• EPA Substance Registry System: 1,4-Dioxaspiro[4.5]decan-8-amine, N,N-bis(phenylmethyl)-(168893-04-7)

Safety Data

• Hazardous Substances Data: 168893-04-7(Hazardous Substances Data)

Usage

General Description

1,4-Dioxaspiro[4.5]decan-8-amine, N,N-bis(phenylmethyl)-, also known as bis(4-benzylaminomethyl)-1,4-dioxaspiro[4.5]decan-8-ylmethyl)benzeneamine, is a chemical compound that belongs to the class of spiro compounds. It is a heterocyclic amine with a spiropentane ring and two benzyl groups attached to the nitrogen atom. 1,4-Dioxaspiro[4.5]decan-8-amine, N,N-bis(phenylmethyl)- has potential applications in organic synthesis and medicinal chemistry due to its unique structure and reactivity. It is important to handle this compound with caution and adhere to proper safety protocols when working with it in a laboratory setting.

Upstream product

• 131511-13-2 4-(N-benzylamino)cyclohexanone ethylene acetal 
• 100-44-7 benzyl chloride 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 100-46-9 benzylamine 
• 103-49-1 dibenzylamine 

Downstream Products

• 1119283-62-3 (trans)-N,N-dibenzyl-4-(4-methylpiperazin-1-yl)cyclohexanamine 
• 883195-12-8 C₂₅H₃₅N₃ 
• 1119283-64-5 C₁₁H₂₃N₃ 
• 1119283-66-7 C₁₆H₃₁N₃O₂ 
• 1119283-68-9 C₁₂H₂₅N₃ 
• 1119284-16-0 C₁₃H₂₅N₃O 
• 1119284-19-3 C₁₃H₂₇N₃ 
• 956928-22-6 N-(1,4-dioxaspiro[4.5]dec-8-yl)-3-(4-fluorophenyl)-3-oxo-thiopropionamide 

Relevant articles and documents

NOVEL DUAL MODE OF ACTION SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND PHOSPHODIESTERASE INHIBITORS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutically acceptable salt, solvate or hydrate thereof, wherein said compound of formula (I) comprises at least one covalently bound -ONO2 or -ONO moiety and at most four covalently bound -ONO2 or -ONO moieties, and wherein AR, R1, X, R3 and R4 are as defined in claim 1; and pharmaceutical compositions thereof, and their use in methods of treating or preventing a disease alleviated by inhibition of PDE5 in a human or in a non-human mammal.

4-AMINO-2-PYRIDO-BICYCLIC PYRIMIDINES AND USE THEREOF AS TOPOISOMERASE II INHIBITORS

The present invention concerns 4-amino-2-pyrido-bicyclic pyrimidines as type II topoisomerase inhibitors and use thereof as medicaments especially in the treatment of cancer. The invention also provides a method for the manufacture of 4- amino-2-pyrido bicyclic pyrimidines.

NEW CYCLOHEXYLAMINE DERIVATIVES HAVING β2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITIES

The present invention relates to novel compounds having β2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.