16900-57-5 Usage
Description
DL-Propargylglycine (PAG) is an organic compound that serves as an irreversible inhibitor of the enzyme cystathionine-γ-lyase (CSE), which is responsible for the synthesis of hydrogen sulphide (H2S), a potent vasodilator and pro-inflammatory mediator. PAG effectively blocks H2S synthesis activity in various biological systems, making it a valuable compound in the study and treatment of H2S-associated conditions.
Uses
Used in Pharmaceutical Industry:
DL-Propargylglycine is used as an inhibitor for the enzyme CSE to study and potentially treat conditions associated with H2S synthesis. By blocking the enzyme, PAG can reduce H2S-associated inflammation in rodent models of pancreatitis, oedema, and endotoxemia, making it a promising candidate for therapeutic applications in these areas.
Used in Chemical Synthesis:
DL-Propargylglycine Hydrochloride is used in the preparation of tert-Butoxycarbonyl Azide, a compound utilized in various chemical reactions and synthesis processes. This application highlights the versatility of PAG in both biological and chemical contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 16900-57-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,0 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16900-57:
(7*1)+(6*6)+(5*9)+(4*0)+(3*0)+(2*5)+(1*7)=105
105 % 10 = 5
So 16900-57-5 is a valid CAS Registry Number.
