169104-31-8

Basic information

• Product Name: (-)-(1R,2S,3R,5R)-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol
• Synonyms: (-)-(1R,2S,3R,5R)-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol
• CAS NO: 169104-31-8
• Molecular Weight: 274.707
• Mol File: 169104-31-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-(1R,2S,3R,5R)-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(1R,2S,3R,5R)-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol(169104-31-8)
• EPA Substance Registry System: (-)-(1R,2S,3R,5R)-3-(5-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol(169104-31-8)

Safety Data

• Hazardous Substances Data: 169104-31-8(Hazardous Substances Data)

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 79200-57-0 (1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxylmethyl)-1-aminocyclopentan hydrochloride 

Relevant articles and documents

STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING

The present disclosure provides STING modulators/agonists, and methods of synthesis and methods for using for the prophylaxis or treatment of cancer and other STING-related diseases. The present disclosure relates to a compound represented by the Formula (I): wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.

INHIBITORS OF E1 ACTIVATING ENZYMES

This invention relates to compounds that inhibit El activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.