169131-88-8

Basic information

• Product Name: (1'R)-phenyl 2'-propenyl 2-butynoate
• CAS NO: 169131-88-8
• Molecular Weight: 200.237
• Mol File: 169131-88-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1'R)-phenyl 2'-propenyl 2-butynoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1'R)-phenyl 2'-propenyl 2-butynoate(169131-88-8)
• EPA Substance Registry System: (1'R)-phenyl 2'-propenyl 2-butynoate(169131-88-8)

Safety Data

• Hazardous Substances Data: 169131-88-8(Hazardous Substances Data)

Upstream product

• 590-93-2 2-Butynoic acid 
• 104713-12-4 (R)-1-phenylprop-2-en-1-ol 

Downstream Products

• 169131-87-7 3-(Z)-chloroethylidene-4S-chloromethyl-5R-phenyl-γ-butyrolactone 

Relevant articles and documents

Template Effect of Pd(II) in the Synthesis of Differently Substituted Enantiopure γ-Butyrolactones and Its Synthetic Applications

Under the catalysis of Pd(II) in the presence of CuX2 and LiX, 1'-substituted allylic 2-alkynoates undergo stereoselective cyclization affording β, γ-disubstituted α-alkylidene-γ-butyrolactones with cis or trans relative configurations.A highly efficient hydrogenation reaction of the cyclization product afforded a trans-α, β-disubstituted-γ-butyrolactone in quantitative yield with high stereoselectivity.Isohomopilopic acid which can be converted into isopilocarpine was synthesized using this methodology by further transformation.