169331-38-8

Basic information

• Product Name: (S)-3-hexylcyclohexanone
• Synonyms: (S)-3-hexylcyclohexanone
• CAS NO: 169331-38-8
• Molecular Weight: 182.306
• Mol File: 169331-38-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (S)-3-hexylcyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-hexylcyclohexanone(169331-38-8)
• EPA Substance Registry System: (S)-3-hexylcyclohexanone(169331-38-8)

Safety Data

• Hazardous Substances Data: 169331-38-8(Hazardous Substances Data)

Upstream product

• 930-68-7 cyclohexenone 
• 592-41-6 1-hexene 
• 44767-62-6 n-hexylmagnesium chloride 

Relevant articles and documents

ASYMMETRIC SYNTHESIS OF ORGANIC COMPOUNDS

The present invention provides processes for the production of chiral compounds in a stereoisomeric excess. The present processes involve reacting a hydrometallated alkene compound with a compound comprising a conjugated-bond system under conditions such

Catalytic asymmetric carbon-carbon bond formation using alkenes as alkylmetal equivalents

Catalytic asymmetric conjugate addition reactions with organometallic reagents are powerful reactions in synthetic chemistry. Procedures that use non-stabilized carbanions have been developed extensively, but these suffer from a number of limitations that prevent their use in many situations. Here, we report that alkylmetal species generated in situ from alkenes can be used in highly enantioselective 1,4-addition initiated by a copper catalyst. Using alkenes as starting materials is desirable because they are readily available and have favourable properties when compared to pre-made organometallics. High levels of enantioselectivity are observed at room temperature in a range of solvents, and the reaction tolerates functional groups that are not compatible with comparable methods-a necessary prerequisite for efficient and protecting-group-free strategies for synthesis.

Catalytic asymmetric conjugate addition of Grignard reagents mediated by copper(I)-chiral bidentate phosphine complex

A catalytic amount of a chiral phosphine I-copper iodide complex catalyzes the conjugate addition of organomagnesium chlorides to cycloalkenones and pentenolide to give the corresponding addition products in 94-72% ee.