16947-82-3

Basic information

• Product Name: BOC-CYS(ET)-OH
• Synonyms: N-ALPHA-T-BUTOXYCARBONYL-S-ETHYL-L-CYSTEINE;N-BOC-S-ETHYL-L-CYSTEINE;BOC-CYSTEINE(ET)-OH;BOC-CYS(SC2H5)-OH;BOC-CYS(ET)-OH;BOC-S-ETHYL-L-CYSTEINE;N-(tert-butoxycarbonyl)-S-ethyl-L-cysteine;Boc-Cys[S-Et]Oh
• CAS NO: 16947-82-3
• Molecular Formula: C₁₀H₁₉NO₄S
• Molecular Weight: 249.33
• Mol File: 16947-82-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 400.3 °C at 760 mmHg
• Flash Point: 195.9 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 1.58E-07mmHg at 25°C
• Refractive Index: 1.5
• Storage Temp.: -15°C
• PKA: 3.58±0.10(Predicted)
• CAS DataBase Reference: BOC-CYS(ET)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-CYS(ET)-OH(16947-82-3)
• EPA Substance Registry System: BOC-CYS(ET)-OH(16947-82-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 16947-82-3(Hazardous Substances Data)

Usage

General Description

BOC-CYS(ET)-OH is a chemical compound containing a BOC (tert-butoxycarbonyl) protecting group, an ethyl (ET) linker, and a cysteine (CYS) residue. It is commonly used in peptide synthesis as a building block for creating peptides with specific sequences. The BOC protecting group serves to protect the amino group of the cysteine residue, while the ethyl linker provides flexibility in the peptide structure. BOC-CYS(ET)-OH is an important tool in the field of biochemistry and pharmaceutical research, as it allows for the manipulation and creation of peptides with diverse functional properties.

InChI:InChI=1/C10H19NO4S/c1-5-16-6-7(8(12)13)11-9(14)15-10(2,3)4/h7H,5-6H2,1-4H3,(H,11,14)(H,12,13)/t7-/m0/s1

Upstream product

• 2629-59-6 S-ethyl-L-cysteine 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Derivative of Kutkin dimer analog JJA-D0 or its pharmaceutically acceptable salt, preparation method and use thereof

The invention relates to a derivative of Kutkin dimer analog JJA-D0 or its pharmaceutically acceptable salt, a preparation method and use thereof. The compound has a structure shown as a general formula (I). According to the invention, an alkyl group, an aryl group, a heteroaryl group, an alkoxycarbonylalkyl group, an acyl group, a sulfonate group, an antioxidant group such as a lipoic acid group,a H2S donor group such as a cysteine group, and a NO donor group such as a nitrate group are introduced to JJA-D0, and a series of structurally novel compounds can be synthesized and disclosed. The compounds inhibit NADPH oxidase and have superior anti-oxidation and anti-inflammatory pharmacological mechanisms by comparing with Kutkin, the compounds also have donor groups that provide NO and H2S,can further enhance pharmacological activity, and can be a new class of multifunctional compounds. The disclosed JJA-D0 derivative can be used for preparing health products or drugs for prevention ortreatment of diseases associated with NADPH oxidase, diseases associated with free radicals, diseases associated with inflammation, diseases associated with NO, and diseases associated with H2S.