169555-93-5 Usage
General Description
FMOC-L-4-PYRIDYLALANINE is a chemical compound that consists of the FMOC (9-fluorenylmethoxycarbonyl) protective group attached to the amino acid L-4-pyridylalanine. FMOC-L-4-PYRIDYLALANINE is commonly used in peptide synthesis, where the FMOC group acts as a temporary protecting group for the reactive amino group of the L-4-pyridylalanine, allowing for selective reactions with other amino acids. FMOC-L-4-pyridylalanine is often employed in the construction of peptide libraries for drug discovery and development, as well as in the study of protein structure and function. Due to its versatile and important role in peptide chemistry, FMOC-L-4-pyridylalanine is a valuable tool for researchers in the field of biochemistry and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 169555-93-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,5,5 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 169555-93:
(8*1)+(7*6)+(6*9)+(5*5)+(4*5)+(3*5)+(2*9)+(1*3)=185
185 % 10 = 5
So 169555-93-5 is a valid CAS Registry Number.
169555-93-5Relevant articles and documents
Potential mechanism-based tyrosine kinase inhibitors. Part 2. Design and synthesis of peptides containing heterocyclic tyrosine analogues
Andrews, David M.,Gregoriou, Mary,Page, Timothy C. M.,Peach, Josephine M.,Pratt, Andrew J.
, p. 1335 - 1340 (2007/10/02)
The Fmoc derivatives of two homochiral tyrosine analogues, a pyridine N-oxide and a pyridone, have been prepared in high stereochemical purity.Solid-phase synthesis has been used to prepare a decapeptide substrate for the tyrosine kinase domain of epidermal growth factor.Two decapeptides, which incorporate the tyrosine analogues in place of tyrosine, and thereby have the potential to act as mechanism-based inhibitors of epidermal growth factor tyrosine kinase, have been synthesised and found to inhibit the aforementioned kinase.
