169873-06-7Relevant articles and documents
Synthesis and Chromatographic Separation of the Stereoisomers of Furnidipine
Alajarin, Ramon,Alvarez-Builla, Julio,Vaguero, Juan J.,Sunkel, Carlos,Casa-Juana, Miguel Fau de,et al.
, p. 617 - 620 (1993)
The four stereoisomers of methyl tetrahydrofuran-2-ylmethyl 2,6-dimethyl-4-(o-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (furnidipine), have been synthesized and separated by chiral chromatography using D-phenylglycine as chiral stationary phase.Enantiomeric purity of stereoisomers is determined by HPLC-CSP technique and configurations deduced via X-ray crystallography.