169892-12-0

Basic information

• Product Name: 5-Heptenal, 7-oxo-7-phenyl-, (5E)-
• CAS NO: 169892-12-0
• Molecular Formula: C13H14O2
• Molecular Weight: 202.253
• Mol File: 169892-12-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 5-Heptenal, 7-oxo-7-phenyl-, (5E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Heptenal, 7-oxo-7-phenyl-, (5E)-(169892-12-0)
• EPA Substance Registry System: 5-Heptenal, 7-oxo-7-phenyl-, (5E)-(169892-12-0)

Safety Data

• Hazardous Substances Data: 169892-12-0(Hazardous Substances Data)

Upstream product

• 111-30-8 Glutaraldehyde 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 142-29-0 cyclopentene 
• 50789-30-5 5,5-dimethoxypentanal 
• 1678-18-8 (2-oxo-2-phenylethyl)-triphenylphosphonium chloride 
• 532-27-4 1-chloroacetophenone 
• 6048-29-9 triphenylphenacylphosphonium bromide 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 514167-97-6 (2E,7E)-9-oxo-9-phenyl-nona-2,7-dienoic acid methyl ester 
• 1429619-06-6 (1R,2R,3R)-2-nitro-3-(2-oxo-2-phenylethyl)cyclohexanol 
• 1449578-92-0 (1S,2R,3R)-2-nitro-3-(2-oxo-2-phenylethyl)cyclohexanol 
• 1449578-93-1 (1R,2S,3R)-2-nitro-3-(2-oxo-2-phenylethyl)cyclohexanol 
• 1429619-25-9 (1S,2S,3S)-2-nitro-3-(2-oxo-2-phenylethyl)cyclohexanol 

Relevant articles and documents

Dual catalyst control in the enantioselective intramolecular Morita-Baylis-Hillman reaction

(Chemical Equation Presented) The intramolecular Morita-Baylis Hillman (MBH) reaction has been achieved with unprecedented levels of enantioselectivity. Using a cocatalyst system involving pipecolinic acid and N-methylimidazole, cyclic MBH products have b

Stereoselective Visible-Light Catalyzed Cyclization of Bis(enones): A Viable Approach to the Synthesis of Enantiomerically Enriched Cyclopentane Rings

Photoredox catalytic cyclization of aryl enones in the presence of visible light, promoted either by metals or organic dyes, represent a valuable strategy for the synthesis of cycloalkanes. The development of a stereoselective version of such transformation, in the presence of the metal-free catalyst Eosin Y was studied, with the aim to realize an efficient protocol for the in-flow synthesis of enantiomerically enriched functionalized cyclopentane rings, taking advantage of the flow reactors technology. The use of a chiral auxiliary on the bisenone to be cyclized offers a straightforward and convenient option to exert a stereocontrol on the light-driven cyclization. By exploiting Evans’ oxazolidinones, the stereoselective light-driven cyclization affords, after the removal of the chiral auxiliary, a functionalized 1,2-trans cyclopentane ring in up to 83/17 enantiomeric ratio. When the reaction was performed in continuo, in a homemade coil photoreactor, high yields were observed. The cyclization was also successfully realized in a 3D-printed mesoreactor, without any change in the diastereoseletctivity of the process.

Intramolecular Tandem Seleno-Michael/Aldol Reaction: A Simple Route to Hydroxy Cyclo-1-ene-1-carboxylate Esters

Intramolecular tandem seleno-Michael/aldol reaction followed by an oxidation-elimination process can be an efficient tool for the construction of hydroxy cyclo-1-ene-1-carboxylate esters from oxo-α,β-unsaturated esters. Generation of lithium selenolate from elemental selenium and n-BuLi provides a simple and efficient one-pot access to cyclic endo-Morita-Baylis-Hillman adducts.