169949-48-8

Basic information

• Product Name: 3-cyano-(R,S)-phenylalanine ethyl ester
• Synonyms: 3-cyano-(R,S)-phenylalanine ethyl ester
• CAS NO: 169949-48-8
• Molecular Weight: 218.255
• Mol File: 169949-48-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-cyano-(R,S)-phenylalanine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyano-(R,S)-phenylalanine ethyl ester(169949-48-8)
• EPA Substance Registry System: 3-cyano-(R,S)-phenylalanine ethyl ester(169949-48-8)

Safety Data

• Hazardous Substances Data: 169949-48-8(Hazardous Substances Data)

Upstream product

• 69555-14-2 ethyl N-diphenylmethylene glycine 
• 28188-41-2 m-(bromomethyl)benzonitrile 
• 169949-49-9 2-(Benzhydrylidene-amino)-3-(3-cyano-phenyl)-propionic acid ethyl ester 

Downstream Products

• 57213-48-6 3-cyano-(D,L)-phenylalanine 
• 214842-56-5 2-[2-(4-Thiocarbamoyl-benzenesulfonylamino)-acetylamino]-3-(3-thiocarbamoyl-phenyl)-propionic acid ethyl ester 
• 214842-42-9 2-[2-(4-Cyano-benzenesulfonylamino)-acetylamino]-3-(3-cyano-phenyl)-propionic acid ethyl ester 

Relevant articles and documents

USP30 INHIBITORS

The application relates to phenyl- or naphthylsulfonamide derivatives of the structural formula (I). The compounds are described as inhibitors of USP30 (ubiquitin specific peptidase 30) useful for the treatment of conditions involving mitochondrial defects including neurodegenerative diseases such as Alzheimer's and Parkinson's or a neoplastic disease such as leukemia.

Design of benzamidine-type inhibitors of factor Xa

A series of derivatives of rac-benzenesulfonyl-glycyl-phenylalanine or its ethyl ester with a combination of thioamido/amidino or amidino/amidino substituents in the benzene rings was synthesized as potential inhibitors of factor Xa (fXa). Among these, th